INTRODUCTION The aim of this report is to present a severe case of phenytoin (PHT)-induced gingival hyperplasia in a Saudi patient. MATERIALS AND METHODS A 12-year-old male epileptic patient, undergoing PHT therapy, was diagnosed clinically with severe gingival hyperplasia. His treatment consisted meticulous oral care and weekly professional prophylaxis. The patient was advised oral folic aci...

Gingival hyperplasia is a frequent complication in transplant patients who receive cyclosporine or calcium channel blockers. We studied an unusual case involving a renal transplant recipient with post-transplant non-Hodgkin's lymphoma that manifested as gingival hyperplasia. We initially consider that it was a side effect of cyclosporine and nifedipine. The lesion did not respond to dose reduct...

background and aims. gingival hyperplasia, a relatively common side effect of antiepileptic and anticonvulsant drugs, occurs in 30‒50% of patients taking phenytoin and 25‒81% of those taking cyclosporine. gingival hyperplasia due to lack of balance between extracellular synthesis and degradation is associated with increased production of il-1b, il-6 and il-8 by gingival fibroblasts. tissue leve...

Gingival hyperplasia can occur during use of drugs such as diphenylhydantoin, cyclosporine and nifedipine. We report, three cases of gingival hyperplasia induced by amlodipine, a second generation calcium channel blocker. Exact cause of induction of thehyperplasia is not known. Individual variation in metabolism of the drug may be a factor.

Many terms have been used to describe gingival overgrowth. The expression gingival hyperplasia (“abnormal increase in the number of normal cells in a normal arrangement in an organ or tissue, which increase in volume”) and gingival hypertrophy (“enlargement or overgrowth of an organ or part due to an increase in size of its constituent cells”) have been also used, although gingival overgrowth i...

Drug-induced gingival hyperplasia is the increased growth of epithelium and submucosa which may cause bleeding loss teeth. Certain anticonvulsant, immunosuppressive, antihypertensive drugs are underlying in most cases. Among them, cases due to amlodipine very rare. Here, we discuss topic along with a case overgrowth induced by amlodipine. A 51-year-old female presented overgrowth. She was on be...

Amlodipine is a calcium channel blocker. Because of its long acting effect it is being widely used as antihypertensive drug. Gingival hyperplasia is one of its side effects. The histological and clinical evidences were consistent with amlodipine-induced gingival hyperplasia. The aim of publishing this report is to draw the attention of dentists towards this adverse effect.

OBJECTIVE The present study aimed to assess the effect of the use of the CO(2) laser on the treatment of gingival hyperplasia in orthodontic patients wearing fixed appliances. BACKGROUND DATA Gingival hyperplasia is a condition very frequent in patients undergoing fixed orthodontic treatment. Amongst the treatments available for this is the use of surgical lasers. METHODS Ten patients enter...