The aim of the present study was to investigate whether a gradually increasing reperfusion algorithm, in which the brief reperfusion was lengthened as the duration of each reperfusion/reocclusion cycle remained fixed, enhances cardioprotection. Rats were randomized into 5 groups: the sham, reperfusion injury (R/I), gradually decreased reperfusion (GDR; 30/10‑25/15‑15/25‑10/30 sec of reperfusion...

BACKGROUND We developed a simple and new insulin resistance index derived from a glucose clamp and a meal tolerance test (MTT) in Japanese patients with type 2 diabetes mellitus. METHODS Fifteen patients [mean age: 53 years, fasting plasma glucose (FPG) 7.7 mmol/L, HbA1c 7.1% (54 mmol/mol), body mass index 26.8 kg/m(2)] underwent a MTT and a glucose clamp. Participants were given a test meal ...

Natural Language Processing (NLP) techniques, such as toponym detection and resolution, are an integral part of most Geographic Information Retrieval (GIR) architectures. Without these components, synonym detection, ambiguity resolution and accurate toponym expansion would not be possible. However, there are many important factors affecting the success of an NLP approach to GIR, including topon...

Geographic Information Retrieval (GIR) has emerged as a new and promising tool for representation, storage, organisation of and access to geographic information. One of the current issues in GIR research is ranking of retrieved documents by both textual and geographic similarity measures. This paper describes an approach that learns GIR ranking functions using Genetic Programming (GP) methods b...

OBJECTIVE To assess the role of adiposity on the pharmacodynamics of basal insulins NPH, detemir, and glargine in type 2 diabetes mellitus (T2DM), as estimated by glucose infusion rate (GIR) and endogenous glucose production (EGP) rate in the euglycemic clamp. RESEARCH DESIGN AND METHODS We examined the variables that best predicted GIR and EGP in 32-h clamp studies after treatment with subcu...

Recent evaluation results from Geographic Information Retrieval (GIR) indicate that current information retrieval methods are effective to retrieve relevant documents for geographic queries, but they have severe difficulties to generate a pertinent ranking of them. Motivated by these results in this paper we propose a novel method to re-order the list of documents returned by a GIR system. The ...

Financial crises are linked to large output declines, but the potential links between different types of crises remains unclear. To enhance understanding we study the interdependencies between domestic banking crises, on one hand, and external financial crises, including currency and sudden stop crises, on the other in a quarterly global panel. We further ask how the different crises relate to ...

Glucose infusion into rats has been shown to sensitize/desensitize insulin secretion in response to glucose. In pancreatic islets from glucose-infused rats (GIR) (48 h, 50%, 2 ml/h) basal insulin release (2.8 mmol/l glucose) was more than fourfold compared with islets from saline-infused controls and the concentration-response curve for glucose was shifted to the left with a maximum at 11.1 mmo...

BACKGROUND In France, the August 2003 heat wave was responsible for considerable excess mortality among the elderly. We wonder whether the dependency level could be a marker of the risk for mortality during this heat wave. METHODS Retrospective cohort study of deaths that occurred between 1 and 20 August 2003, conducted in five departments in the Paris area (Ile-de-France) among the beneficia...