A previous survey for glucose-6-phosphate dehydrogenase (G6PD) deficiency among the Saudi Arab population residing along the Persian Gulf perimeter revealed a high frequency of the enzyme defect among subjects from oasis areas. The investigation reported was undertaken to supplement the previous study using a screening test with the same reliability as the conventional Motulsky brilliant cresyl...

Glucose-6-phosphate dehydrogenase (G6PD) deficiency is one of the most common inherited enzymopathies in endemic areas of malaria including Southeast Asia. The molecular features of G6PD deficiency are similar among Southeast Asian population, with differences in the type of the prominent variants in each region. This study determined the prevalence and molecular characteristics of G6PD deficie...

The enzyme profiles of 109 Bolivian stocks of Trypanosoma cruzi were determined by cellulose acetate electrophoresis using the four enzymes: malate dehydrogenase (oxaloacetate decarboxylating) (NADP+) (E.C.1.1.1.40, ME), phosphogluconate dehydrogenase (E.C.1.1.1.44, 6PGDH), phosphoglucomutase (E.C.2.7.5.1, PGM) and glucosephosphate isomerase (E.C.5.3.1.9, GPI). As previously, two principal zymo...

The effect of several dose levels of estradici valerate on the activities of 6 enzymes and the levels of nucleic acids and certain lipids was studied in a transplantable lactating mammary adenocarcinoma, R3230AC, as well as in the mammary glands of the same tumor-bearing animals. Estrogen treatment caused a doserelated increa.se in the activities of glucose-6-phosphate dehydrogenase, malate deh...

The evolutionary conservation of a housekeeping gene such as G6PD is greater than that of tissue-specific genes, presumably because the latter may require more specific adaptation to the physiology of individual organisms. The abundance of distinct mutation sites and their clinical manifestations make G6PD ideal for structure-function analysis. Therefore, it is of interest to screen of G6PD def...

in the 1980’s, medium-chain acyl-coa dehydrogenase deficiency (mcadd) was first described in the literature as three children who presented with coma, hypoglycemia, hyperammonemia, and fatty liver while fasting. these symptoms while similar to reye’s syndrome, were found to be due to an inability to metabolize medium chain fatty acids during fasting periods. fatty acids are utilized by the body...

seizure is a rare presentation for acute hemolysis due to g6pd deficiency. we report a previously healthy boy who presented initially with seizure and cyanosis and subsequently acute hemolysis, due to glucose-6-phosphate dehydrogenase deficiency (g6pd) and probably secondary methemoglobinemia, following the ingestion of fava beans.