background: diabetes mellitus is a chronic disease. decreasing postprandial hyperglycemia by retarding glucose absorption through inhibiting carbohydrates digesting enzymes (α-amylase and α-glucosidase) is one of many approaches used for the management of this disease. this study was aimed at evaluating the normoglycaemic potential of helianthus annuus leaf. methods: the effect of the in vitro ...

in an attempt to develop alternative medicine for the treatment of diabetes and related complications, the antidiabetic potential of the fruits of c rataegus pinnatifida was evaluated. the antidiabetic potential of the methanol (meoh) extract as well as different solvent soluble fractions of the fruits of c . pinnatifida was evaluated via α-glucosidase, protein tyrosine phosphatase 1b (ptp1b), ...

objective: alpha-glucosidase, as a carbohydratase catalyses the liberation of alpha-glucose from the nonreducing end of some carbohydrates from foods in digestive tract.  consequently, retard absorption of glucose by the inhibition of carbohydrate hydrolyzing enzymes is one of the therapeutic approaches to decrease the postprandial hyperglycemia. recently, a great deal of attention has been pai...

Background:α-Glucosidase Inhibition can significantly prevent glucose uptake after meal, and helps in controlling of some adverse effects in diabetics. So determination of α-Glucosidase inhibitory effect and antioxidant activity of the Haplophyllum acutifolium and Ferula haussknechtii aerial organs was the aim of this study.Methods:Inhibitory effect of hexane extracts from dif...

Background:α-Glucosidase Inhibition can significantly prevent glucose uptake after meal, and helps in controlling of some adverse effects in diabetics. So determination of α-Glucosidase inhibitory effect and antioxidant activity of the Haplophyllum acutifolium and Ferula haussknechtii aerial organs was the aim of this study.Methods:Inhibitory effect of hexane extracts from dif...

The study was aimed to determine the antioxidant and α-glucosidase inhibition activities of the stem and leaf of five different traditional medicinal plants. The studied plants exhibited varied antioxidant and α-glucosidase inhibition activities. The antioxidant activities of the plants were determined through their free radical scavenging capabilities using DPPH assay. The most potent antioxid...

Objective: Alpha-glucosidase, as a carbohydratase catalyses the liberation of alpha-glucose from the nonreducing end of some carbohydrates from foods in digestive tract.  Consequently, retard absorption of glucose by the inhibition of carbohydrate hydrolyzing enzymes is one of the therapeutic approaches to decrease the postprandial hyperglycemia. Recently, a great deal of attention has been pai...

The present study was designed to determine the effects of the essential oil of Laurusnobilis L. (Lauraceae) and its three main components on α-glucosidase and reactive oxygenspecies scavenging activity. The chemical composition of the essential oil from Laurus nobilisL. leaves was analyzed by GC/GC-MS and resulted in the identification of 29 compounds,representing 99.18% of the total oil. 1,8-...

The present study was designed to determine the effects of the essential oil of Laurusnobilis L. (Lauraceae) and its three main components on α-glucosidase and reactive oxygenspecies scavenging activity. The chemical composition of the essential oil from Laurus nobilisL. leaves was analyzed by GC/GC-MS and resulted in the identification of 29 compounds,representing 99.18% of the total oil. 1,8-...

A number of unusual and rare carbohydrates were tested as potential inhibitors of various glycosidases, as well as inhibitors of N-linked oligosaccharide processing. The best inhibitors of several arylglycosidases and of glucosidase I were L-xylulose and L-fructose. Both of these sugars showed some inhibitory activity towards yeast alpha-glucosidase but were inactive against beta-glucosidase an...