Seven independently isolated glutathione reductase-deficient (gor) Escherichia coli mutants were found to have an in vivo glutathione redox state that did not significantly differ from that of the parental strain, 98 to 99% reduced. Strains containing both a gor mutation and either a trxA mutation (thioredoxin deficient) or a trxB mutation (thioredoxin reductase deficient) were able to maintain...

results and conclusions the analysis of covariance revealed that catalase activity significantly decreased in the copenhagen football test group after the assessment compared to regular football exercises group. meanwhile, the glutathione reductase values significantly increased (p < 0.05). the increase in glutathione reductase values led to the protection of erythrocyte metabolism through the ...

Glutathione reductase (EC 1.6.4.2) was purified from intact pea (Pisum sativum) chloroplasts by a method which includes affinity chromatography on ADP-agarose. Fractions from the affinity column which had glutathione reductase activity consisted of polypeptides of 60 and 32 kilodaltons. Separation of the proteins by electrophoresis on native gels showed that glutathione reductase activity was a...

Abbreviations: ROS: Reactive oxygen species; H2O2: Hydrogen peroxide; CAT: Catalase; POD: peroxidase; APX: Ascorbic Acid Peroxidase; GR: Glutathione Reductase; AsA-GSH: Ascorbate-Glutathione; ASC: Reduced form of Ascorbate; DHA: Dehydroascorbate; MDHAR: Monodehydroascorbate Reductase; DHAR: Dehydroascorbate reductase; GSH: Reduced Glutathione; GSSG: Oxidized Glutathione; PDA: Potato Dextrose Ag...

Thioredoxin reductase and glutathione reductase are important enzymes of redox system that help the malaria parasite to maintain an adequate intracellular redox environment and contribute greatly to the antioxidant capacity of the cell. In the present study humoral immune response directed against thioredoxin reductase and glutathione reductase during Plasmodium berghei infection were investiga...

background: exercise can change the release of numerous cytokines and modulate their receptor systems. dietary ω-3 lipids may decrease the levels of inflammatory cytokines and prostaglandins (pgs). therefore, in this study, we investigated the effects of exercise and eicosapentaenoic acid (epa) supplementation, with or without vitamin e, on the blood levels of il-2, tnf-α, catalase, glutathione...

Human glutathione reductase (NADPH + GSSG + H+ in equilibrium with NADP+ + 2 GSH) is a suitable enzyme for correlating spectroscopic properties and chemical reactivities of protein-bound FAD analogues with structural data. FAD, the prosthetic group of the enzyme, was replaced by FAD analogues, which were modified at the positions 8, 1, 2, 4, 5 and 6, respectively, of the isoalloxazine ring. Whe...

Nitric oxide (NO) modulates plant response by post-translationally modifying proteins, mainly through S-nitrosylation. Ascorbate peroxidase (APX) in the ascorbate-glutathione (AsA-GSH) cycle participates removal of hydrogen peroxide (H2O2). However, relationship between S-nitrosylation and role tomato APX (SlAPX) under nitrate stress is still unclear. In this study, enzyme activity, mRNA expres...

Malaria parasites adapt to the oxidative stress during their erythrocytic stages with the help of vital thioredoxin redox system and glutathione redox system. Glutathione reductase and thioredoxin reductase are important enzymes of these redox systems that help parasites to maintain an adequate intracellular redox environment. In the present study, activities of glutathione reductase and thiore...