results histopathologically, a decrease (statistically not significant) in the thickening of alveolar or bronchial wall, formation of fibrous bands, and superimposed collagen were noted in the animals in group b as compared to the animals in group a. conclusion in this experimental study, administration of gla one hour before thoracic irradiation may be a protective agent against radiation-indu...

The aim of the present study was to look into the possible protective effects of glycyrrhizic acid (GA) against isoproterenol-induced acute myocardial infarction in Sprague-Dawley rats. The effect of three doses of glycyrrhizic acid in response to isoproterenol (ISO)-induced changes in 8-isoprostane, lipid hydroperoxides, super oxide dismutase and total glutathione were evaluated. Male Sprague-...

objective: much attention is paid to angiogenesis due to its mutual role in health and disease. therefore, the effect of various chemical and physical agents on inhibition of this process has been recently studied. this study was conducted to investigate the synergic effect of glycyrrhizic acid and electromagnetic field on angiogenesis. materials and methods: in this experimental study, 44 ross...

Licorice is a medicinal plant showing many therapeutic activities. Its roots contain numerous pharmacologically active compounds such as a triterpenoid saponin--glycyrrhizic acid and an isoflavan--glabridin. There are reports indicating that glabridin exhibits estrogen-like activity, therefore it can be classified into phytoestrogens, which may soothe menopause symptoms including postmenopausal...

OBJECTIVE Much attention is paid to angiogenesis due to its mutual role in health and disease. Therefore, the effect of various chemical and physical agents on inhibition of this process has been recently studied. This study was conducted to investigate the synergic effect of glycyrrhizic acid and electromagnetic field on angiogenesis. MATERIALS AND METHODS In this experimental study, 44 Ross...

To establish a method for determination of glycyrrhizic and glycyrrhetinic acids in Weiyanning Granule. The contents of glycyrrhizic and glycyrrhetinic acids are determined by HPLC under conditions as follows: Diamonsil C18 (4.6 mm × 250 mm, 5 μm) column, mobile phase of acetonitrile-0.05 mol/L ammonium acetate solution (A: 0.05 mol/L ammonium acetate solution; B: acetonitrile, gradient elution...

To investigate responses of Glycyrrhiza glabra var. glabra and G. glabra var. glandulifera to molybdenum and salicylic acid, we measured four stress biochemical parameters: anthocyanin, nitric acid, glycyrrhizic acid and peroxidase activity in callus tissues. Callus tissues obtained from seedlings root cultures were treated by 60 mg. l-1 molybdenum and 5 µM salicylic acid alone or together for...

The extraction and separation conditions of glycyrrhizic acid and glabridin from licorice were investigated. By changing the different extraction solvents, procedures, times and temperature, the optimum extraction condition was established: the used of ethanol/water (30:70, v/v) as an extraction solvent, and 60 min dipping time under 50 degrees C. The extracts of licorice were separated and det...