Gold nanoparticle assemblies possess diverse application potential, ranging from industrial nanotechnology to medical biotechnology. Because the structures and properties of assemblies are directly affected by the stabilization mechanism between the organic molecules serving as protecting ligands and the gold nanoparticle surface, it is crucial to find and investigate new stabilization mechanis...

The Genomes On Line Database (GOLD) is a comprehensive resource that provides information on genome and metagenome projects worldwide. Complete and ongoing projects and their associated metadata can be accessed in GOLD through pre-computed lists and a search page. As of September 2007, GOLD contains information on more than 2900 sequencing projects, out of which 639 have been completed and thei...

Are you aware that 41% of completely sequenced microbial genomes remain unpublished? Where can scientists find this information? The answer is provided by Siezen and Wilson’s (2008) genomic update section article on unpublished, yet publicly available microbial genomes. The authors highlight that the GOLD (Genome OnLine Database, http://www.genomesonline.org) provides a complete and updated sta...

This unit describes the preparation of conjugates between nanometer-scale gold particles and synthetic oligonucleotides. Oligonucleotide-functionalized gold nanoparticles are finding increased use in both the construction of complex, tailored nanostructures and the optimization of DNA sequence analysis. The protocols in this unit outline the synthesis, purification, and characterization of nano...

Colloidal gold is very attractive for several applications in biotechnology because of its unique physical and chemical properties. Many different synthesis methods have been developed to generate gold nanoparticles (AuNPs). Here, we will introduce these methods and discuss the differences between fabrication techniques. We will also discuss ecofriendly synthesis methods being developed to effi...

Evaldas Stankevicius and co-workers (article number 2100027) demonstrate the formation of large-scale gold microbump arrays generating hybrid lattice plasmon polaritons in visible to near-infrared range using direct laser writing technique. The demonstrated method shows relevant technological progress metallic gratings by a cost-effective laser-based It provides new opportunities for polariton ...

Precise control over the structure of metal nanomaterials is important for developing advanced nanobiotechnology. Assembly methods of nanoparticles into structured blocks have been widely demonstrated recently. However, synthesis of nanocrystals with controlled, three-dimensional structures remains challenging. Here we show a directed crystallization of gold by a single DNA molecular regulator ...

M. MOSHFEGH, H. FOROOTANFAR, B. ZARE, A.R. SHAHVERDI, G. ZARRINI, M.A. FARAMARZI 0F Department of Pharmaceutical Biotechnology, Faculty of Pharmacy and Biotechnology Research Center, Tehran University of Medical Sciences, P.O. Box 14155-6451, Tehran, 14174, Iran Department of Pharmaceutical Biotechnology, Faculty of Pharmacy, Pharmaceutics Research Center, Herbal and Traditional Medicine Resear...

DNA melting and hybridization is a fundamental biological process as well as a crucial step in many modern biotechnology applications. DNA confined on surfaces exhibits a behavior different from that in free solutions. The system of DNA-capped gold nanoparticles exhibits unique phase transitions and represents a new class of complex fluids. Depending on the sequence of the DNA, particles can be...