نتایج جستجو برای: graft disparity
تعداد نتایج: 99853 فیلتر نتایج به سال:
Racial differences on the outcome of simultaneous pancreas and kidney (SPK) transplantation have not been well studied. We compared mortality and graft survival of African Americans (AA) recipients to other racial/ethnic groups (non-AA) using the national data. We studied a total of 6585 adult SPK transplants performed in the United States between January 1, 2000 and December 31, 2007. We perfo...
Earlier studies reported inferior outcomes among black compared with white kidney transplant (KT) recipients. We examined whether this disparity improved in recent decades. Using the Scientific Registry of Transplant Recipients and Cox regression models, we compared all-cause graft loss among 63,910 black and 145,482 white adults who received a first-time live donor KT (LDKT) or deceased donor ...
BACKGROUND AND OBJECTIVES The Statewide Sharing variance to the national kidney allocation policy allocates kidneys not used within the procuring donor service area (DSA), first within the state, before the kidneys are offered regionally and nationally. Tennessee and Florida implemented this variance. Known geographic differences exist between the 58 DSAs, in direct violation of the Final Rule ...
Delayed engraftment or graft failure is one of the major complications after cord blood transplantation (CBT). To investigate factors impacting engraftment, we conducted a retrospective analysis of adult patients who underwent reduced-intensity CBT at our institute, in which preparative regimens mainly consisted of fludarabine, melphalan, and total body irradiation with graft-versus-host (GVH) ...
A disparity remains between graft survival of renal allografts from deceased donors and from living donors. A better understanding of the molecular mechanisms that underlie this disparity may allow the development of targeted therapies to enhance graft survival. Here, we used microarrays to examine whole genome expression profiles using tissue from 53 human renal allograft protocol biopsies obt...
conclusions the x-intercepts (point at which the fdc crosses the x-axis) were on average more in the base-in direction, y-intercepts (point at which the fdc crosses the y-axis) were shifted in the exo direction, and slopes were steeper in the symptomatic group. results there were more subjects with exo fixation disparity than eso fixation disparity in the study sample. the means for fixation di...
Disparity for HLA in unrelated donor bone marrow transplantation (BMT) increases the risk of graft rejection and graft-versus-host disease (GVHD) and may compromise transplant outcome. We have compared the outcome of matched and mismatched transplants from unrelated donors in 137 children with acute lymphoblastic leukemia (ALL). Their disease status was complete remission (CR)-1, 24 patients; C...
PROBLEM The effect of donor/recipient age disparity on living-donor renal graft function is controversial. The objective of this study is to find new clinical predictors of renal graft function and evaluate the effect of donor/recipient age disparity in our series. METHODS A retrospective review of our institutional renal transplantation database was performed. We calculated the glomerular fi...
This brief review will summarise our present knowledge on the possible role of human minor histocompatibility antigens (mHags) in graft failure. Following a short introduction on the possible nature of human mHags some in vitro studies dealing with graft failure and rejection will be discussed. To understand the possible impact of mHag disparity between organ donor and recipient on the outcome ...
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