Granulomatosis with polyangiitis (GPA) is characterised by granulomatous necrotising inflammatory lesions of the upper and lower respiratory tract, often associated with pauci-immune glomerulonephritis. The diagnosis of granulomatosis with polyangiitis is made according to the classification criteria of the ACR criteria for granulomatosis with polyangiitis. We present two cases of granulomatosi...

The causes of multiple pulmonary nodules in a pediatric patient include infections, malignancies, sarcoidosis, granulomatosis with polyangiitis (GPA; formerly Wegener’s granulomatosis), eosinophilic granulomatosis with polyangiitis (EGPA; formerly Churg Strauss), hypersensitivity pneumonitis, and lymphomatoid granulomatosis. The clinician is faced with the challenging task of combining clinical...

Classical Wegener's granulomatosis is a relentlessly progressive and rapidly fatal disease. A pulmonary 'limited form' is associated with a much better prognosis. We report 3 cases of Wegener's granulomatosis which ran a prolonged indolent course despite major manifestations outside the lower respiratory tract and review the literature on survival.

Takanobu Kan'", Shun$uke Takahagi'", Akiko Kamegashira', Hiroshi Ooiwa^ Takashi YaguchP and Michihiro Hide'* 'Department of Dermatology, Programs for Biomédical Researcii, Division of Molecular Medicai Science, Graduate School of Biomédical Sciences, -Department of Clinicai Immitnoiogy and Rlieumatology, Hiroshima University, 1-2-3 Kasumi, Minami-ku, Hiroshima 734-8551, and ^Medical Mycology Re...

Department of Otorhinolaryngology, Head and Neck Surgery, University of Kiel, Kiel, Germany. Please address correspondence to: Martin Laudien, MD, Department of Otorhinolaryngology, Head and Neck Surgery, University of Kiel, Arnold-Heller-Straße 14, 24105 Kiel, Germany. E.mail: [email protected] Received on February 8, 2010; accepted on February 17, 2010. Clin Exp Rheumatol 2010; 28 (Supp...