The purpose of present study was to investigate the effect of water and ethanol extracts of red grape seeds on inhibition of pancreatic -amylase and lipase in vitro. Total proanthocyanidins were determined in grape seed extracts (GSEs). Different concentrations (400, 800, 1300 and 1800 ppm) of each GSE were employed to evaluate their potentials on pancreatic -amylase and lipase after pre-incuba...

conclusions the data indicated that co-administration of grape seed extract and exercise training had more significant effects than exercise training or grape seed extract alone; this may constitute a convenient and inexpensive therapeutic approach to diabetic vascular complications. results the endothelium dependent vasorelaxation to acetylcholine was reduced significantly in diabetic animals;...

In one study, 287 patients diagnosed with asymptomatic carotid plaques or abnormal plaque free carotid intima-media thickness (CIMT) were randomly assigned to a GSE group (n = 146) or control group (n = 141). As anticipated, after treatment, GSE resulted in significant reduction in MMCIMT progression, while MMCIMT and plaque score were stable and even increased with the control group. The numbe...

Grape-seed proanthocyanidins’ role as stimulators of active GLP-1 in rats suggests that they could be effective as satiating agents. Wistar rats were used to study the effects of proanthocyanidins on food intake with different doses, administration times and proanthocyanidin extract compositions. A dose of 423 mg of phenolics per kg body weight (BW) of grape-seed proanthocyanidin extract (GSPE)...

The crude seed extract of neem, black pepper, mahogani, and garlic bulb with three doses were evaluated against legume pod borer in the country bean field in two seasons kharif 2006 and rabi 2006-2007. The neem seed extract applied @150 and 100 g/l and mahogani seed extract @ 100 g/l of water 7 days intervals on the country bean showed better performance in the reduction of flower and pod damag...

Grape seed extract has been proven to exert anticancer effects on different tumors. These effects are mainly ascribed to catechin and procyanidin content. Analytical studies demonstrated that grape seed extract composition is complex and it is likely other components could exert biological activities. Using cell count and flow cytometry assays, we evaluated the cytostatic and apoptotic effects ...

The aerial parts of Vitis vinifera Linn. (Common grape, Hindi ⎯ Angur) have been widely used in Ayurveda to treat a variety of common and stress related disorders. The seed extract of grapes was evaluated by Sreemantula and others for antistress activity in normal and stress induced rats. Furthermore, the extract was studied for nootropic activity in rats and in vitro antioxidant potential to c...

many studies have been performed for treatment or prevention of pulmonary fibrosis. however, no effective treatment has been found yet. the aim of this study was to investigate the effect of grape seed extract on bleomycin-induced lung fibrosis in rat. hydroalcoholic extract of grape seed (vitis vinifera) was prepared using maceration method. nmri rats weighing 250-300 g were given single intra...

    Many studies have been performed for treatment or prevention of pulmonary fibrosis. However, no effective treatment has been found yet. The aim of this study was to investigate the effect of grape seed extract on bleomycin-induced lung fibrosis in rat. Hydroalcoholic extract of grape seed (Vitis vinifera) was prepared using maceration method. NMRI rats weighing 250-300 g were given...