Multiply inverted balancer chromosomes that suppress exchange with their homologs are an essential part of the Drosophila melanogaster genetic toolkit. Despite their widespread use, the organization of balancer chromosomes has not been characterized at the molecular level, and the degree of sequence variation among copies of balancer chromosomes is unknown. To map inversion breakpoints and stud...

In this issue of Academic Emergency Medicine, Schoenfeld et al. report a qualitative analysis of Shared decision-making (SDM) from the perspective of Emergency Department (ED) patients. Shared decision-making is "a collaborative process in which patients and providers make health care decisions together, taking into account the best evidence available, as well as the patient's values and prefer...

Server Farms have gained popularity for providing scalable and reliable computing / Web services. A load balancer plays a key role in this architecture, serving as a “traffic cop” to direct the requests to suitable servers. Selecting and using the proper load balancer to match the characteristics of the servers will have a significant performance impact. This paper examines some commonly used l...

The balancers of Drosophila melanogaster are widely used in genetic research. By analyzing the phenotype of offspring from hybridization of chapped wing (L) mating with OR, 982p and e, respectively, we mapped the chapped wing mutation on chromosome 3 for the first time and demonstrated the chapped wing mutation as a new balancer of D. melanogaster with dominant wing nicking phenotype. Finally, ...

Balancer chromosomes are important tools for a variety of genetic manipulations in lower model organisms, owing to their ability to suppress recombination. In mouse, however, such effort has not been accomplished, mostly due to the size of the chromosomes and the complexity of multiple step chromosomal engineering. We developed an effective and versatile cassette-shuttling selection (CASS) stra...

by Kyle Bruce Wheeler Network intrusion detection systems (NIDS) are deployed near network gateways to analyze all traffic entering or leaving the network. The traffic at such locations is frequently transmitted in such volumes and speeds that a commodity computer quickly becomes overwhelmed. NIDS must be able to handle all of the traffic available. The SPANIDS platform addresses this problem w...

I present the sandpile load balancer, an application of the abelian sandpile model to dynamic load balancing. The sandpile load balancer exploits the self-organized criticality of the abelian sandpile model to distribute web traffic across a network of servers. I also propose the sandpile load balancer latency minimization problem in which the goal is to minimize the latency of packets across t...

the russian foreign policy toward various issues is often combined with complexity, ambiguity and conflicts. this fact was true at least in the history of relations between iran and russia, so that russian face is depicted as an unreliable partner for the iranian citizens and elites. with the importance of this issue, the study aims to answer this central question: what are the reasons for thes...

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