Using an explant culture system, we have demonstrated that human somatotropes respond to growth hormone releasing factor (GRF) and somatostatin (SRIF) from as early as 9.5 weeks of fetal age. Responsiveness to GRF increases significantly as a function of age up to midgestation while SRIF inhibition of basal growth hormone (GH) release does not change. SRIF has little effect on GRF-stimulated GH...

GH-releasing factor (GRF) is the hypothalamic peptide that stimulates both synthesis and secretion of GH. The GRF signal is transduced to somatotroph cells through pituitary GRF receptors and generates episodic bursts of GH secretion into the bloodstream. Secretion of GH is highly sexually dimorphic, particularly in the rat [1]. In female rats, GH surges are of lower amplitude and occur more ir...

Despite extensive research on running mechanics, there is still a knowledge gap with respect to the degree of relationship between mediolateral ground reaction forces (ML-GRF) and foot pronation. Our goal was to investigate whether differences exist in ML-GRF among runners that exhibit different degrees of pronation. Seventeen male and 13 female recreational runners ran with and without shoes w...

Glutinous rice flour (GRF) and glutinous rice starch (GRS) were modified by dry-heat treatment and their rheological, thermal properties and freeze-thaw stability were evaluated. Compared with the native GRF and GRS, the water-holding ability of modified GRF and GRS were enhanced. Both the onset and peak temperatures of the modified samples increased while the endothermic enthalpy change decrea...

Exogenous growth hormone-releasing factor (GRF) has been shown to activate feeding by central mechanisms involving the suprachiasmatic nucleus/medial preoptic area (SCN/MPOA). Until now, however, the role played by endogenous GRF in the SCN/MPOA in naturally occurring eating has remained unknown. To investigate this, the effects of SCN/MPOA injections of GRF antiserum (AS-GRF) on feeding in rat...

in this paper, we introduce the concept of rarely generalized regular fuzzy continuous functions in the sense of a.p. sostak's and ramadan is introduced. some interesting properties and characterizations of them are investigated. also, some applications to fuzzy compact spaces are established.

The Gibbs random field (GRF) has proved to be a simple and practical way of parameterizing the Markov random field, which has been widely used to model an image or image-related process in many image processing applications. In particular, the GRF can be employed to construct an efficient Bayesian estimation that often yields optimal results. We describe how the GRF can be efficiently incorpora...

Asymmetries in sagittal plane knee kinetics have been identified as a risk factor for anterior cruciate ligament (ACL) re-injury. Clinical tools are needed to identify the asymmetries. This study examined the relationships between knee kinetic asymmetries and ground reaction force (GRF) asymmetries during athletic tasks in adolescent patients following ACL reconstruction (ACL-R). Kinematic and ...

peptide that specifically stimulates both synthesis and secretion of pituitary GH [1]. GRF is released into the hypophyseal-portal vessels under control by a variety of neurotransmitters and neuropeptides. After reaching the pituitary, GRF binds to its specific receptors [1] on somatotrophs and generates bursts of GH secretion episodically [2]. Earlier ligand-binding and functional studies in r...