Objective(s): Scorpion venom has toxic effects on mammals, insects and crustaceans.  Toxicogenic peptides are major contributors to the scorpion venom, which make it toxic. The Hemiscorpius lepturus (H. lepturus) is one of the most common scorpion bites agent, and responsible for 95% of scorpion bite deaths cases in Iran.Materials and Methods:</strong...

The available Razi Institute antivenom is still, empirically, used by intramuscular (IM) administration for the treatment of scorpion stings in humans by six medically dangerous species including Hemiscorpius lepturus (H. lepturus). The aim of this study was to assess the neutralizing ability and effectiveness of the antivenom in inhibiting hemoglobinuria, biochemical changes, increased microal...

BACKGROUND Hemolyis of red blood cells is a serious toxic effect commonly found among patients envenomed by Hemiscorpius lepturus scorpion. OBJECTIVES The aim of the present study was to evlaute the efficay of the avaible polyvalent antivneom in preventing this phenomena. MATERIALS AND METHODS Using a red blood cell fragility test, the anti-hemolytic effectiveness of a new antivenom serum a...

Scorpionism is a known significant problem of medical and social importance in many tropical and subtropical regions including the Middle East. In Iran, highest prevalence of scorpion sting about 60% of all the stings has been reported from Khuzestan province. Among the 21,000 cases of reported scorpion stung patients, 12% were caused by H. lepturus, but contributed to 95% of all moralities in ...

scorpionism is a known significant problem of medical and social importance in many tropical and subtropical regions including the middle east. in iran, highest prevalence of scorpion sting about 60% of all the stings has been reported from khuzestan province. among the 21,000 cases of reported scorpion stung patients, 12% were caused by h. lepturus, but contributed to 95% of all moralities in ...

scorpionism is a known significant problem of medical and social importance in many tropical and subtropical regions including the middle east. in iran, highest prevalence of scorpion sting about 60% of all the stings has been reported from khuzestan province. among the 21,000 cases of reported scorpion stung patients, 12% were caused by h. lepturus, but contributed to 95% of all moralities in ...

BACKGROUND Scorpion sting is a public health problem in Khuzestan, South-West Iran. The aims of the current study were to monitor the hospitalized children, due to scorpion sting, and releasing more clinical and epidemiologic data related to scorpionism in this Province. METHODS In this retrospective study, the data of scorpion sting victims, among the hospitalized children in Abuzar Children...

Scorpion stings are a common and important health problem in Iran, particularly in south and southwestern Iran, including the province of Khuzestan. In the area of Khuzestan near the city of Ramhormoz, Hemiscorpius lepturus (Scorpionida: Hemiscorpioiidae) and Androctonus crassicauda (Buthidae) are present. Ramhormoz is in southwestern Iran and is one of the most important foci of the scorpion s...

Background: GABAergic interneurons in the hippocampal CA1 area are mutually communicated by gap junctions (GJs) composed of connexin36 (Cx36). We examined the role of Cx36 in CA1 in manifestation of kindled seizures and hippocampal kindling in rats. Methods: Quinine, as the specific blocker of Cx36, was injected into CA1, and kindled seizures severity was examined 10 min afterward. Moreover, qu...