Our aim was to determine whether the increase in serum pancreatic lipase values, reported in patients with chronic renal failure maintained on haemodialysis, is the result of haemoconcentration by fluid removal during dialysis, or whether it is due to lipase stimulation by endothelial lipoprotein lipase, induced by the heparin used as an anticoagulant. We therefore compared the increases in ser...

High blood ureas have been found in untreated cases (Schloss, 1918; Bessau, Rosenbaum and Leichtentritt, 1922; Cohen, Miller and Kramer, 1933), and Schloss considered that haemoconcentration was not enough to account for this finding. By means of the phenolsulphonphthalein test and Ambard's coefficient of urea excretion he showed that the function of the kidney was impaired in a group of infant...

This retrospective study describes 4 cases of canine babesiosis with histologically confirmed acute pancreatitis. In addition, 16 dogs with babesiosis are reported with serum amylase (>3500 U/l) and/or lipase (>650 U/l) activity elevations of a magnitude that would support a diagnosis of probable acute pancreatitis, although extra-pancreatic sources of the enzymes could not be excluded in these...

In the 1970s scientific research focussed for the first time on dramatic rises in mortality every winter, and on smaller rises in unusually hot weather. Following the recent decline in influenza epidemics, approximately half of excess winter deaths are due to coronary thrombosis. These peak about two days after the peak of a cold spell. Approximately half the remaining winter deaths are caused ...

Cholera presents a picture of mixed salt and water depletion, its most outstanding feature being dehydration with consequent haemoconcentration and peripheral circulatory failure. A patient may lose fluid enormously, and in very bad cases we have observed the plasma reduced as low as to one half its volume though the total blood volume was not markedly altered. Treatment consists mainly in repl...

Despite the widespread use of hypothermia in clinical surgery, the nature of the plasma electrolyte changes associated with this state is far from clear, and little attempt has been made to consider them in relation to adrenocortical activity. Haemoconcentration has been recorded in hypothermia by Rosenhain and Penrod (1951), Millar (1954), and Villalobos, Adelson, and Barila (1955), although S...

Ovarian hyperstimulation syndrome (OHSS) is a severe complication of ovarian stimulation for assisted reproductive techniques. Clinical manifestations are massive extravascular fluid accumulation and haemoconcentration. Vascular endothelial growth factor (VEGF) has been demonstrated to mediate the development of OHSS. Intravenous albumin at the time of oocyte aspiration has been suggested as an...