OBJECTIVE While chronic cerebrospinal venous insufficiency (CCSVI) can be characterized using cervical plethysmography, much remains unknown about the haemodynamics associated with this procedure. The aim of the study was therefore to gain a deeper understanding of the observed haemodynamics. METHOD Forty healthy controls and 44 CCSVI patients underwent cervical plethysmography, which involve...

Computational fluid dynamics techniques have been applied to study both the local and the global haemodynamics created by different surgical reconstructions, currently used to treat complex congenital heart defects. These operations are characterised by competition of flows which can lead to postoperative failure of the surgical treatment. Different techniques have been used in order to improve...

Effects of 12 months steroid treatment on pulmonary haemodynamics in 24 patients with pulmonary sarcoidosis, stage II and III, were investigated. All patients had a chest radiograph, lung function tests, and pulmonary haemodynamics (measured at rest and during submaximal exercise) prior to the treatment. Resting pulmonary hypertension was found in 3 patients. In 18 an abnormal increase in pulmo...

AIMS To compare serum concentrations and effects on respiratory mechanics and haemodynamics of salbutamol administered by small volume nebuliser (SVN) and metered dose inhaler (MDI) plus spacer. METHODS Blinded, randomised, crossover study in 12 intubated infants and children (mean age 17.8 months) receiving inhaled salbutamol therapy. Subjects received salbutamol as 0.15 mg/kg by SVN and fou...

BACKGROUND Massive liver necrosis, characteristic of acute liver failure, may affect hepatosplanchnic haemodynamics, and contribute to the alterations in renal haemodynamics and function. AIMS To investigate the relation between hepatosplanchnic haemodynamics, including portal systemic shunting, and renal blood flow and function in rats with acute liver failure. METHODS Liver failure was in...

The arterial blood pressure is mainly determined by the cardiac output and the total peripheral resistance. The blood pressure and the cardiac output are measured and the total peripheral resistance is calculated by dividing mean arterial blood pressure by cardiac output. This calculation is valid only for laminar flow in rigid straight tubes, but still this calculation is currently used to est...

AIMS Actual resuscitation guidelines recommend 10 respirations per minute (rpm) for advanced pediatric life support. This respiratory rate (RR) is much lower than what is physiological for children. The aim of this study is to compare changes in ventilation, oxygenation, haemodynamics and return of spontaneous circulation (ROSC) rates with three RR. METHODS An experimental model of asphyxial ...