Leishmania donovani in India causes visceral infection (kala-azar) and dermal infection (post-kala-azar dermal leishmaniasis). We report here the identification of polymorphism in a well-defined genetic locus among the Leishmania parasites causing the visceral and dermal manifestations, in a comparison of 15 post-kala-azar dermal leishmaniasis and 12 kala-azar patient isolates.

BACKGROUND An improved understanding in transmission variation of kala-azar is fundamental to conduct surveillance and implementing disease prevention strategies. This study investigated the spatio-temporal patterns and hotspot detection for reporting kala-azar cases in Vaishali district based on spatial statistical analysis. METHODS Epidemiological data from the study area during 2007-2011 w...

N. Shokri 1, , E. Azizi , H. Akbari Javar 1, , Sh. Fouladdel , A. Khalaj 3 and R. Dinarvand 1, 4 Department of Pharmaceutics , Faculty of pharmacy, Tehran University of Medical Sciences, Tehran, Iran Molecular Research Lab , Department of Pharmacology and Toxicology, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran Department of Medicinal Chemistry , Faculty of Pharmacy,...

BACKGROUND & OBJECTIVE Of the two reservoirs of infection of kala-azar i.e., patients of kala-azar and post kala-azar dermal leishmaniasis (PKDL), PKDL provides easy access for the sandfly to pick up the parasites. In the last epidemic of 1977 in India, the importance of PKDL as a potential cause of increase in number of kala-azar cases was ignored. During recent years, we found an increase in ...

Navid Freidoonimehr 1, Mohammad Mehdi Rashidi 2,3, Shirley Abelman 4,* and Giulio Lorenzini 5 1 Young Researchers & Elite Club, Hamedan Branch, Islamic Azad University, 65181-15743, Hamedan, Iran; [email protected] 2 Shanghai Key Lab of Vehicle Aerodynamics and Vehicle Thermal Management Systems, Tongji University, Shanghai 201804, China; [email protected] 3 ENN-Tongji Clean Energ...

uncommon but grave complication. During the recent outbreak of kala-azar in Calcutta that commenced after the Bengal famine of 1943. increasing numbers of seriously complicated cases of kala-azar were seen (Sen Gupta, 1947) and one of the grave complications was pneumococcal meningitis. During the last two years, 1945 and 1946, four cases of kala-azar who had developed this complication were ad...

In the Indian Medical Gazette for June 1927, Chopra, Gupta, and David described a new serum test for kala-azar. These workers observed that when certain organic compounds of antimony were brought in contact with the serum from kala-azar patients in a miniature testtube, a thick flocculent precipitate was formed at the junction of the two; whereas with nonkala-azar sera no such precipitation occ...

1. Rogers L. The epidemic malarial fever of Assam, or kala-azar, successfully eradicated from tea garden lines. Br Med J. 1898; 2:891–2. 2. Price JD, Rogers L. The uniform success of segregation measures in eradicating Kala-azar from Assam tea gardens: it is bearing on the probable mode of infection. BMJ. 1914;1:285–9. http://dx.doi. org/10.1136/bmj.1.2771.285 3. Kaul SM, Sharma RS, Borgohain B...

BACKGROUND There is limited reliable information on abortion in Iran, where abortion is illegal and many women of reproductive age seek clandestine abortion to end their unintended pregnancy. This study aims to examine the determinants of induced abortion in the city of Hamedan, Iran. METHODS The study utilizes recent data from the 2015 Hamedan Survey of Fertility, conducted in a representati...