Background: HbAlc reflects longer-term glycemic control and having the edge to be less influenced by acute stress. Several studies demonstrated the prognostic role of HbAlc in elective PCIand acute MI patients treated with thrombolytic therapy. However, the impact of HbAlc level on prognosis in STEMI patients successfully treated with primary PCI has not been explicitly examined. Purpose: We as...

OBJECTIVE Glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide are incretin hormones, secreted in response to meal ingestion. The incretin hormones stimulate insulin secretion and are essential for the maintenance of normal plasma glucose concentrations. Both incretin hormones are metabolized quickly by the enzyme dipeptidyl peptidase-IV (DPP-IV). It is well known th...

OBJECTIVES Dipeptidyl peptidase IV (CD26; E.C. 3.4.14.5) is plasma membrane glycoprotein exopeptidase. There are no data on both phenotypic or genotypic expression and polymorphism of DPP-IV in Indian type-2 diabetic patients. Therefore we estimated the dipeptidyl peptidase IV (DPP-IV) levels in Indian type 2 diabetic population. METHODS Selection of study group was as follows: 1. Twenty seve...

OBJECTIVES The optimal treatment of latent autoimmune diabetes in adults (LADA) is not established. We explored whether early insulin treatment, which has shown beneficial effects in rodents and in human pilot studies, would result in better preservation of β-cell function or metabolic control, compared with conventional treatment. SUBJECTS AND METHODS Glucagon-stimulated C-peptide and HbAlc ...

OBJECTIVE Osteoprotegerin (OPG) acts as an important regulatory molecule in atherosclerosis. Recent studies report that thiazolidinediones could affect OPG expression. We investigated the relationship between OPG and inflammatory cytokines and the effects of pioglitazone (a PPARγ (PPARG) agonist) versus metformin on serum OPG levels in type 2 diabetic patients. DESIGN AND METHODS Sixty-seven ...

The objective of this study was to explore the practicability of using process and outcome indicators to routinely assess the quality of diabetes care. Health care data of diabetic patients using antidiabetic drugs older than 40 years old in 2006-2008 were retrieved from an electronic information system of Phramongkutklao Hospital, Thailand. The process and outcome indicators were taken from th...

Glycosylated hemoglobin (HbAlc) is most often used as an intermediate indicator for blood glucose control in diabetics, and the Diabetes Control and Complications Trial (DCCT) [1], United Kingdom Prospective Diabetes Study (UKPDS) [2] and Kumamoto Study [3] have greatly valued HbAlc as an indicator for blood glucose control. However, HbAlc levels are influenced by other factors in addition to b...