Background: Thalassemia patients are more susceptible to hepatitis than the normal population due to the frequent blood transfusions. Objective: To determine the immune response of children with major ß-thalassemia, by measuring anti-hepatitis B surface antibody (anti-HBs Ab) following the last HBV vaccine injection. Methods: This study was carried out on 215 thalassemic children who received t...

To evaluate the immune response to hepatitis B vaccination in stable hemodialysis (HD) patients, a retro-prospective investigation was conducted on 68 HD patients. Participants were vaccinated against hepatitis B virus with an intramuscular hepatitis B vaccination schedule, 40 micrograms at 0, 1, and 6 months. The serum antibody level against hepatitis B surface antigen (HBs) in HD patients was...

Human hemoglobins (Hbs) are known to be immunogenic, and both normal and variant forms of Hb have been shown to stimulate antibody formation in a variety of animal species. In patients who are homozygous for the sickle Hb (HbS) mutation, transfusion of normal, HbA-containing erythrocytes provides a potential stimulus for HbA alloimmunization. We tested serum samples for the presence of anti-Hb ...

background: hepatitis b virus is one of the most common causes of chronic liver diseases. vaccination is the best way of prophylaxis and is of utmost importance. this study was conducted to compare the prophylactic effect of intradermal and intramuscular injection of hepatitis b vaccine. methods: a blind randomized clinical trial was performed among subjects who presented to the infectious dise...

OBJECTIVE To investigate the prevalence of antibodies to human immunodeficiency virus (HIV), hepatitis B virus (HBV) and hepatitis C virus (HCV), and of hepatitis B surface (HBs) antigen in commercial sex workers (CSW) who attended a sexually transmitted disease (STD) clinic in Tokyo. METHODS Surveys were conducted on 308 CSW and 384 control subjects for HIV antibody or 241 control subjects f...

unresponsiveness to hepatitis b surface antigen (hbsag) has been shown to be associated with dysfunction of the presenting cells (apc) and defect in the specific b-lymphocyte and/or t-lymphocyte repertoires.   direct determination of the frequency of specific t-lymphocytes together with complementary analysis of the naive circulating immune cells could provide valuable information about the cel...

background: hepatitis b infection is a major public health problem worldwide. given that immune response towards the vaccine is not perfect, we aimed to evaluate circumstances of immune response in vaccinated students. materials and methods: in this study, 219 medical students of ardabil university of medical sciences were recruited, who had been administered vaccine series for the first time, ...