Today, chronic viral hepatitis is considered as a public health problem in the world. Totally, 5% of the world population, especially in Asia and Africa suffer from this problem. The prevalence of acute hepatitis in America is 0.1-0.2 percent, 50% of those with hepatitis C (HCV) and 5-10% of them with hepatitis B (HCV) develop chronic hepatitis. Determining HBV and HCV genotypes is important to...

BACKGROUND AND OBJECTIVES Hepatitis C virus (HCV) infection is a worldwide concern and it is the major cause of liver disease. Several genotypes of the HCV have been reported from different regions of the world. The determination of the HCV genotypes is important for the prediction of response to antiviral treatment and clinical outcomes. So, HCV genotyping in each region is of great importance...

Hepatitis C virus (HCV) is a major global health problem and one of the most common causes of chronic liver diseases. The current study was carried out to investigate the ability of High Resolution Melting (HRM) method in HCV genotyping. 40 HCV-Positive sera with unknown and 12 sera with known HCV genotypes were collected from different clinical laboratories in Tehran as well as Rasht in north ...

background and objectives: hepatitis c virus (hcv) infection is a worldwide concern and it is the major cause of liver disease. several genotypes of the hcv have been reported from different regions of the world. the determination of the hcv genotypes is important for the prediction of response to antiviral treatment and clinical outcomes. so, hcv genotyping in each region is of great importanc...

BACKGROUND/AIM Several types of the hepatitis C virus (HCV), with variations in different parts of the genome, have been isolated from different regions of the world. Based on heterogenic sequences in the isolated genome, HCV is classified into different genotypes and subtypes. Data on distribution of HCV genotypes in a certain region could be important to patient management. Therefore, this st...

The hepatitis C virus (HCV) infection among patients undergoing haemodialysis is high. The aim of this study was to identify the HCV genotypes among chronic haemodialysis patients who were HCV positive in Guilan province, northern Islamic Republic of Iran. All patients on haemodialysis at Guilan haemodialysis centres were enrolled. Enzyme-linked immunosorbent assay and polymerase chain reactio ...

HCV genotypes have been documented in clinical practice. The aim of this study was to determine the replication priority of different HCV genotypes in a Chinese HCV positive cohort. Serum samples from 491 apparently healthy Chinese blood donors testing positive for HCV antibodies and naive to antiviral drug therapy were tested. Genotyping analysis showed that genotypes 1b and 2a were predominan...

BACKGROUND/AIM The natural history of hepatitis C virus (HCV) infection is variable and the factors determining the course of the illness are unclear. There are geographical variations in the distribution of different HCV genotypes, and some of them are related to the specific infection routes. Regarding our country, the dominant genotype is genotype 1b. It is unclear and still remains a questi...

results of 1818 hcv rna positive samples, hcv genotypes pcr fragments were detected in 1552 (85.5%) samples. hcv genotype 3a was the predominant genotype (39.4%) followed by genotype 2a (24.93%). hcv genotype 3 was the predominant genotype in punjab and sindh regions, while genotype 2 was the most predominant genotype in khyber pakhtunkhwa region and the second predominant genotype after genoty...

conclusions there were significant linkages between hcv genotypes and il28b genotypes/alleles. patients with a favorable il28b and genotypes 1 and 4 hcv infection stand a better chance to clear hcv in the acute phase. objectives this meta-analysis was designed to determine the world-wide distribution patterns of il28b genotypes and alleles, and to find possible linkages between il28b and hcv ge...