Recent studies suggest improved outcomes and survival in obese heart failure patients (i.e., the obesity paradox), although obesity and heart failure unfavorably alter cardiac function and metabolism. We investigated the effects of weight loss on cardiac function and metabolism in obese heart failure mice. Obesity and heart failure were induced by feeding mice a high-fat (HF) diet (60% kcal fro...

background: physical symptoms are often associated with poor quality of life (qol) in patients with heart failure (hf). progressive impairment in the ability ofperforming routine physical activities of daily lifeand decrease inexercise tolerance is thought to lead to the worsening of physical symptoms. exercise and physical activity can improve functional capacity, and improve the symptoms asso...

Introduction: We aimed at evaluating the clinical, laboratory and echocardiography effects of intracoronary administration of autologous bone marrow stem cell transplantation in different clinical entities of chronic Heart Failure (HF) patients.   Methods: This procedure was carried out during an interventional study conducted in the Cardiology department from JAN 2012 to APR 2013. The HF ...

Cardiovascular disease (CVD), especially heart failure (HF) as its common final pathway, is the leading cause of morbidity and mortality worldwide. Furthermore, oxidative and inflammatory processes represent fundamental underlying mechanisms for the development and progression of HF. Of interest, in recent years the development of markers with diagnostic and prognostic value for this pathology ...

conclusions the effectiveness of nursing education on self-care behaviour of hf patients was clearly demonstrated. methodological differences in development and implementation of education programs, made the comparison between the results of the studies difficult. results the findings of the reviewed studies showed that self-care behaviour of patients who received nursing education improved sig...

We investigated cardio-respiratory coupling in patients with heart failure by quantification of bidirectional interactions between cardiac (RR intervals) and respiratory signals with complementary measures of time series analysis. Heart failure patients were divided into three groups of twenty, age and gender matched, subjects: with sinus rhythm (HF-Sin), with sinus rhythm and ventricular extra...

Cardiovascular magnetic resonance (CMR) has become a reference standard for the measurement of cardiac volumes, function, and mass. This study aims to reconstruct three dimensional modeling of the left ventricle (LV) in patients with heart failure (HF) using CMRtools and thereby derive the LV functional indices. CMR images were acquired in 41 subjects (6 females) with heart failure (HF) and 12 ...

Patients with heart failure or OSA (obstructive sleep apnoea) have reduced HF-HRV (high-frequency heart rate variability), indicating reduced cardiac vagal modulation, a marker of poor prognosis. CPAP (continuous positive airway pressure) abolishes OSA in patients with heart failure, but effects on daytime HF-HRV have not been determined. We hypothesized that, in patients with heart failure, tr...

The thermal unimolecular dissociation of CH3F was studied in shock waves by monitoring the UV absorption of a dissociation product identified as CH2F. It is concluded that, under conditions applied, the formation of this species corresponds to a minor, spin-allowed, dissociation channel of about 3% yield. Near to the low-pressure limit of the reaction, on the other hand, the energetically more ...

Trimethylamine N-oxide (TMAO), a gut-related metabolite, is associated with heart failure (HF) outcomes. However, TMAO the final product of complex metabolic pathway (ie, choline/carnitine) that has never been entirely investigated in HF. The present study investigates panel metabolites involved TMAO-choline/carnitine for their associations outcome acute HF patients. In total, 806 plasma sample...