*Corresponding author: Dr. Daryoush Shahbazi-Gahrouei, Dept. of Medical Physics and Medical Engineering, Isfahan University of Medical Sciences, Isfahan, Iran. Fax: +98 311 6688597 E-mail: [email protected] carcinoma after thyroidectomy (1-6). In this therapy method, the prescription of sodium iodine is done orally (7). Radioiodine is a beta emitting radionuclide with a physical half life ...

introduction: radioiodine therapy is an effective method for treating thyroid cancer carcinoma, but it has some affects on normal tissues, hence dosimetry of vital organs are important to weigh the risks and benefits of this method. the aim of this study is to measure the absorbed doses of important organs by mcnp (monte carlo n particle) simulation and comparing the results of different method...

Background: Radioiodine therapy has proven to be an effective method in the treatment of patients with differentiated thyroid carcinoma after thyroidectomy. The scope of this study is to describe a method to obtain the dose of organs using medical internal radiation dosimetry (MIRD) method. At the end, the results of MIRD calculations were compared with thermoluminescent dosimeter (TLD...

Background: Reliable estimation of radiation-absorbed dose is necessary to evaluate the benefits and the risks of radiopharmaceuticals used for diagnostic or therapeutic purposes in nuclear medicine. Materiel and Methods: This study included 47 patients treated with iodine-131 for Graves’ disease. A comparative study between Geant4 Monte Carlo simulation and MIRD formalism was carried out to ev...

This paper describes the mathematical efficiency calibration of the whole-body counter at Forschungszentrum Jülich using Monte Carlo codes and mathematical anthropomorphic phantoms. As a prerequisite for the Monte Carlo simulations a precise model of the 4 high-purity germanium (HPGe) detectors had to be developed. Because the technical data provided by the manufacturer were not sufficient for ...

Relation to high absorption fraction of Tc sestamibi by kidneys in heart scan and these organs are near to generation organs (Ovaries and uterus). Urinary system (kidneys and urinary bladder) are specified as sources organs. The main object of this study is to determine the absorbed dose in these critical organs. we have set amount of absorbed fraction radiopharmaceutical in position of kidneys...

BACKGROUND RADIOIODINE IS ROUTINELY USED OR PROPOSED FOR DIAGNOSTIC AND THERAPEUTIC PURPOSES: (123)I, (125)I and (131)I for diagnostics and (125)I and (131)I for therapy. When radioiodine-labelled pharmaceuticals are administered to the body, radioiodide might be released into the circulation and taken up by the thyroid gland, which may then be an organ at risk. The aim of this study was to com...

Introduction: Spatial dose distribution around the radionuclides sources is required for optimized treatment planning in radioimmunotherapy. At present, the main source of data for cellular dosimetry is the s-values provided by MIRD. However, the MIRD s-values have been calculated based on analytical formula in which no electrons straggling is taken to account. In this study, we used Geant4-DNA...