BACKGROUND AND OBJECTIVES Among the array of microangiopathies that may occur during pregnancy, HELLP syndrome and thrombotic thrombocytopenic purpura (TTP) produce similar laboratory findings (hemolytic anemia and thrombocytopenia), although neurological symptoms prevail in TTP and abnormal liver function in HELLP syndrome. It is clinically important to distinguish the two entities given that ...

Plasma exchange therapy has been successfully used in selected patients with hemolysis, elevated liver enzymes, and low platelets (HELLP) syndrome who have organ failure or refractory to treatment. There is no prospective study regarding plasma exchange and its effect in HELLP syndrome. The aim of this study was to investigate the effects of early postpartum use of plasma exchange in patients w...

abstract the first time weinstein in 1982 described patients with the syndrome of hemolysis, elevated liver enzymes, and low platelet count (hellp) in pregnant preeclamptic and eclamptic patients. this syndrome is a severe form of preeclampsia or eclampsia. usually hellp syndrome occurs at the third trimester and only 15% occur before the 27th week of pregnancy and rarely before the 20th week o...

Insufficient invasion of the spiral arteries by trophoblast cells is associated with the etiology of pre-eclampsia, the syndrome of hemolysis, elevated liver enzymes and low platelet counts (HELLP) and pre-eclampsia-associated intrauterine growth restriction (IUGR). Mannose-binding lectin (MBL) is a component of the innate immune system. MBL-mediated activation of the complement cascade is an i...

Introduction: L'objectif de ce travail etait d'étudier et comparer les paramètres épidémiologiques, cliniques, paracliniques et évolutifs des patientes présentant un HELLP syndrome complet et incomplet. (Hemolysis, Elevated Liver enzymes, Low Platelets count). Méthodes: Une enquête rétrospective sur la période du 1er janvier 2005 au 31octobre 2008 et incluant tous les cas de HELLP syndrome coll...

• Vol 8 • March 2006 Postpartum Liver Rupture and HELLP Syndrome Hepatic rupture with hemoperitoneum is a rare but devastating complication of pregnancy, mostly associated with the synd drome of severe gestational hypertension hemolysis, elevated liver enzyme levels, and low platelet count, known as the HELLP syndrome. We describe a young woman with HELLP syndrome and hepatic subcapsular ruptur...

Background: Objective of current study was to determine the incidence of HELLP syndrome in patients with eclampsia and its impact on maternal and perinatal outcome. Methods: The prospective study was conducted in the department of obstetrics and gynaecology, Burdwan medical college, Burdwan on 727 eclamptic mothers, admitted from January 2012 to December 2013. Clinical data and detailed investi...

PURPOSE We report here, the morphological characteristics of the retina and choroid in a patient with hemolysis, elevated liver enzymes, low platelets (HELLP) syndrome, who was not aware of her pregnancy before visiting our hospital. METHODS Case report. RESULTS The patient complained of visual disturbances in both eyes for a few days. Extensive serous retinal detachment and hyperreflective...

Unexpected rapid maternal death after delivery due to HELLP syndrome is rarely encountered and may become the subject of forensic expertise. Unexpectedness, suddenness, and fulminant course of this syndrome as well as absence of classical signs of pre-eclampsia can confuse physicians and lead to diagnostic delay. A definitive post-mortem diagnosis of HELLP syndrome in questionable cases of mate...

OBJECTIVE HELLP syndrome is a severe form of preeclampsia, characterized by hemolysis (H), elevated liver enzymes (EL), and low platelets (LP), whose pathogenesis is unclear. Autoimmunity is thought to play an important role. After the observation of development of type 1 diabetes in a patient with HELLP syndrome, we assumed a possible disease association based on autoimmune reactions. RESEAR...