نتایج جستجو برای: helper cells
تعداد نتایج: 1389355 فیلتر نتایج به سال:
the differential activation of th1 and th2 cells using mafosfamide (mafo) was investigated in vitro in a rat model of alloreactivity. the results of this study are compatible with the hypothesis that mafo, like its parent compound cyclophosphamide, is selectively active against th2-type t-helper cells when administered at low doses (
Asthma is a chronic inflammatory disorder of the airways, associated with airway re-modeling and hyperresponsiveness. It is expressed that asthma influences about 300 million people around the world, which is estimated to increase to about 400 million by 2025. The prevalence rate is 15 to 20 percent in children and 5 to 10 percent in adults, while its trend is still increasing. Inflammation pla...
Introduction: Interleukin-2 (IL-2) as a T helper type 1 (Th1) cytokine has an important role Background and Objective: Interleukin-2 (IL-2) as a T helper type 1 (Th1) cytokine has an important role in activation, growth and differentiation of several immune cells. Moreover IL-2 is known as a pro-inflammatory and anti-tumoral cytokine. In addition deysregulation of IL-2 in some diseases such as ...
The technique of velocity sedimentation at unit gravity was used to determine the size and rosette-forming ability of helper cells in nonimmune and immune C57BL/6 mice. Helper T cells were assayed by the ability to cooperate with bone barrow (B) cells in the antibody response to sheep erythrocytes (SRBC) in vivo. 19S helper cells in nonimmune animals were nonrosette-forming small lymphocytes; a...
twenty-two recipients of hla-nonidentical living related and nonrelated renal allografts were studied for alterations in the relative percentage of okt4-positive peripheral blood t-cells after transplantation. characteristic shifts in the ratio of t-helper to t -suppressor/cytotoxic cells (th/ts-c), but not absolute cell numbers, were demonstrated to correspond with the status of the allograft....
Antigen-specific helper T cells are required in the generation of cytotoxic T cells from thymocyte precursors. We have demonstrated that these alloantigen-specific helper cells can be generated in vitro and that both the quantity and quality of the helpers appear to be superior to the help obtained from unprimed spleen cells. Optimal helper cell activity is produced at day two of culture when C...
introduction: interleukin-2 (il-2) as a t helper type 1 (th1) cytokine has an important role background and objective: interleukin-2 (il-2) as a t helper type 1 (th1) cytokine has an important role in activation, growth and differentiation of several immune cells. moreover il-2 is known as a pro-inflammatory and anti-tumoral cytokine. in addition deysregulation of il-2 in some diseases such as ...
Differentiation of porcine T helper cells is still poorly investigated, partly due to a lack of monoclonal antibodies (mAbs) specific for molecules involved in this process. Recently, we identified a mAb specific for porcine CD27 and showed that CD27 is expressed by all naïve CD8α- T helper cells but divides CD8α+ T helper cells into a CD27+ and a CD27- subset. In the present study, detailed ph...
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