Background: COVID-19 infection can be especially severe in certain risk populations such as patients with hematologic malignancies.

EDITORIAL article Front. Oncol., 17 August 2023Sec. Hematologic Malignancies Volume 13 - 2023 | https://doi.org/10.3389/fonc.2023.1273598

EDITORIAL article Front. Oncol., 17 August 2021Sec. Hematologic Malignancies Volume 11 - 2021 | https://doi.org/10.3389/fonc.2021.744009

Cancer and especially hematological cancer during pregnancy is infrequent and its management is difficult for patients and their families, but also for their physicians since two lives with different priorities have to be considered. Treatment should adhere the standard treatment for the specific type and stage of cancer. Small adaptations can be considered in order to avoid adverse effects on ...

T HE p53 HAS BEEN CHOSEN as molecule of the year for 1993 by the journal Science.' The protein's illustrious history began quietly in 1979, when a 53-kD eukaryotic protein was shown to bind to SV40 large T The protein was named p53 because of its size. Initial studies suggested that p53 was an oncogene because it could transform rodent ~ e l l s . ~ ' ~ The p53 genes used in these studies h...

The expression of CD44 was upregulated in some hematological malignancies and is associated with metastasis and prognosis. The ligation of CD44 with specific monoclonal antibodies can trigger terminal differentiation of leukemic blasts in some subtypes, so it is probable to develop an anti-CD44 based differentiation therapy in leukemia. The effects of CD44 and its monoclonal antibodies are disc...

Although home care (HC) of cancer patients is a common practice, so far only limited efforts have been made to define its role in the global management of patients suffering from malignant blood disorders, who are mainly treated in hospital or in outpatient clinics. HC has not been intensively applied in the treatment of these malignancies, this approach having been traditionally reserved for t...

I. HODGKIN’S LYMPHOMA A. Presentation 1. Subjective. Classical Hodgkin’s disease or Hodgkin’s lymphoma (HL) usually presents as painless lymphadenopathy in the cervical and/or supraclavicular regions. Isolated subdiaphragmatic lymphadenopathy or organ involvement is rare. Although staging studies reveal mediastinal adenopathy in more than 85% of patients, symptoms of cough, chest pain, dyspnea,...

BACKGROUND Human T-lymphotropic virus type 1 (HTLV-1) was the first retrovirus identified in human. The current evidence is quite scarce regarding the potential role of HTLV-1 in pathogenesis of hematologic disorders and non-hematologic malignancies. OBJECTIVES The aim of this study is to evaluate the prevalence of HTLV-1 infection in patients with hematologic disorders and non-hematologic ma...

Hematologic malignancies complicating pregnancy are uncommon, but a delay in diagnosis or treatment can mean the difference between life and death. It is the responsibility of the obstetrician, nurse-midwife, or nurse practitioner to maintain a high index of suspicion when patients present with unexplained lymphadenopathy or protracted constitutional symptoms. Management of these patients requi...