OBJECTIVE Copper deficiency has been reported to cause hematological disorders. However, its clinical and hematological characteristics are not fully understood. Therefore, we investigated bedridden patients suffering from copper deficiency and tried to clarify the clinical features of hematological disorders caused by this condition. PATIENTS AND METHODS Five patients with typical copper def...

Adoptive cell therapy (ACT) is rapidly migrating from bench to clinical therapy for hematological malignancies. Recently, a new subtype of memory T cells, stem cell memory T (TSCM) cells, was shown to be one of the most favorable subsets for ACT. TSCM has high self-renewal capacity and is associated with superior T cell engraftment, persistence, and antitumor immunity. In this review, we focuse...

CONTEXT AND OBJECTIVE Transcranial Doppler (TCD) detects stroke risk among children with sickle cell anemia (SCA). Our aim was to evaluate TCD findings in patients with different sickle cell disease (SCD) genotypes and correlate the time-averaged maximum mean (TAMM) velocity with hematological characteristics. DESIGN AND SETTING Cross-sectional analytical study in the Pediatric Hematology sec...

Lotus (Nelumbo nucifera Gaertn.) is a well known medicinal plant. The extracts of rhizomes, seeds, flowers and leaves have been reported to have varied therapeutic potential. Flowers are traditionally used to treat diarrhoea, cholera, fever, hepatopathy, hyperdipsia and many bleeding disorders. Furthermore, N. nucifera can be used for antidiabetic. This study was aimed to investigate the effect...