BACKGROUND Hepatitis B virus (HBV) vaccination is a well-known, safe and effective way for protection against HBV infection; however, non-responders remain susceptible to infection with HBV. This is so important in patients with any kind of chronic liver disease, especially chronic hepatitis C virus (HCV) patients in whom acute HBV infection may lead to decompensation of liver disease. Some of ...

BACKGROUND Conventional hepatitis B virus (HBV) vaccination fails to achieve efficient protection in about 5-10% of the world population. Hence, different strategies have been adopted to ameliorate HBV antibody titers. This study aimed to evaluate the concurrent application of tetanus-diphtheria (Td) and HBV vaccination on hepatitis B surface (HBs) antibody titer in low-responder healthy indivi...

background: hepatitis b virus (hbv) vaccination is a well-known, safe and effective way for protection against hbv infection; however, non-responders remain susceptible to infection with hbv. this is so important in patients with any kind of chronic liver disease, especially chronic hepatitis c virus (hcv) patients in whom acute hbv infection may lead to decompensation of liver disease. some of...

BACKGROUND Egypt is considered a region of the intermediate prevalence of hepatitis B virus (HBV) infection (4.5%). Seroprotection is assured when hepatitis B surface antibody (HBsAb) levels are ≥ 10 mIU/mL. Our study aimed to evaluate and compare the long-term immunogenicity and efficacy of the recombinant hepatitis B (HB) vaccine. METHODS A cross-sectional study was done for children aged f...

BACKGROUND The duration of protection following primary series vaccination against hepatitis B is unknown in children and adolescents. It has been shown that the level of anti-hepatitis B surface antigen antibodies (anti HBs Ab) declines over years after vaccination. OBJECTIVES The aim of this study was to estimate the long-term immunity against hepatitis B virus infection among children and ...

conclusions the significant number of coinfected hiv-hcv patients only had hbcab positive test without detectable hbv-dna. further studies for detection of hbv-dna in both serum and liver biopsy specimens may help clarify the impact of hbv infection in coinfected hiv/hcv patients. results of 103 hiv-hcv coinfected patients, both hbsag and hbcab were positive in 7 patients (6.8%), negative in 44...

BACKGROUND & AIMS The systematic use of rapid tests performed at points-of-care may facilitate hepatitis B virus (HBV) screening and substantially increase HBV infection awareness. The aim of this study was to evaluate the effectiveness of such tests for HBsAg and anti-HBsAb detection among individuals visiting a variety of healthcare centers located in a low HBV-prevalent area. METHODS Three...

RATIONALE Tumor chemotherapy could weaken the immune system of patients, which might enhance the body sensitivities to the exogenous pathogens, among which the hepatitis B virus (HBV) infection should be concerned because of the higher chances of infection and the severe outcomes, especially in East Asia. The titer level of hepatitis B surface antibody (HBsAb) higher than 10 IU/L is considered ...

conclusions the results showed a declining trend in anti-hbsab titers over the time after vaccination against hepatitis b virus in our region. further studies are warranted to establish the need for a booster dose in cases that are at risk of hepatitis b virus infection. results hepatitis b seroprotection rates (anti hbsab ≥ 10 iu/l) among vaccinated children and adolescents aged 1 and 18 years...

BACKGROUND AND AIMS The duration of the protection of hepatitis B vaccination for infants and the necessity of a booster dose administration is unknown. The aim of the present study was to evaluate the persistence of seroprotection after hepatitis B virus (HBV) vaccination in order to determine the necessity of a single booster dose in 5- to 7-year-old children. METHODS This clinical trial st...