results the mean age of pregnant women was 27.2 ± 5.6 years. the overall seroprevalence of anti-hev was 7.4%. there was a significant association between anti-hev seropositivity and age (p < 0.001), degree of education (p = 0.017), number of household members (p = 0.002), siblings (p = 0.005), and parities (p = 0.007). however, no significant relationship was observed between positive anti-hev ...

type e hepatitis is caused by an unclassified virus producing acute self-limited hepatitis in different parts of the world. in order to estimate the prevalence of hepatitis e virus seropositivity in tehran blood donors, a cross– sectional study was performed by the enzyme immunoassay method from 2003 to 2004 in a group of 90 blood donors. we noticed that 7 cases (7.8%) were anti-hev ab positive...

background hepatitis e virus (hev) infection is a self-limited hepatitis and the most common cause of acute adult hepatitis in asia. young adults and middle-aged populations are more likely to be infected than other age groups. objectives the aim of this study was to determine the seroprevalence of anti-hev among injection drug users (idus) compared to non-idus. patients and methods this was a ...

conclusions in this study, the optimized truncated orf2 protein was expressed in e. coli successfully and the highly purified protein was obtained, which can be a potential vaccine candidate and as an antigen in elisa to diagnose hev infections. results the subcloning was confirmed by pcr, restriction enzyme digestion, and dna sequencing of recombinant plasmid pet30a-orf2.2. the results obtaine...

conclusions the analysis indicates that the hev isolated from blood donors in the southwest of iran belongs to genotype 1. however, more samples from other geographic regions of iran are needed to confirm these findings. because transmission of hev by administration of blood or blood components is likely to occur, it may be sensible to screen donor blood for hev to eliminate transfusion-transmi...

conclusions this study provides support for the hypothesis that humans are probably infected after contact with swine sources. the findings emphasize the importance of checking the country of origin of swine and of improving sanitary control measures from the veterinary standpoint to prevent the spread of hev infection in italy. materials and methods a total of 327 hev sequences of swine and hu...

Some studies have suggested that hepatitis E virus is more frequent in human immunodeficiency virus (HIV) patients and can progress to chronic infection. We aimed to determine the prevalence of hepatitis E virus antibodies and RNA in a series of 100 HIV-infected patients in Tehran, Iran, with comparison to 52 healthy HIV, hepatitis B and C-negative blood donors as controls. HIV-infected patient...

dna coding for the core antigen from hepatitis b virus (hbcag) was amplified, cloned and propagated in e. coli. the core protein was expressed in e. coli and the product was readily detected by western blot. this protein can be used as a diagnostic material in serum screening tests. to increase the level of expression of this antigen in bacteria, two plasmids were constructed in which the gene ...

Swine hepatitis E virus is a newly identified potentially zoonotic virus from pigs of particular concern for possible direct transmission to a human xenotransplant recipient by organ transplantation. In the present study, prevalence of serum antibodies to hepatitis E virus was examined in Canadian swine herds. A total of 998 serum samples collected from 6-month-old healthy slaughter hogs were e...