Previous studies have demonstrated that alpha-tocopheryl hemisuccinate (TS) protects hepatocyte suspensions from chemical-induced toxicity. It has been suggested that TS cytoprotection is related to unique properties of the TS molecule or is dependent on the cellular release and activity of unesterified alpha-tocopherol (T). To test the unique cytoprotective nature of TS in vivo, the protective...

Introduction: Hepatic diseases remain the leading cause of death worldwide. Despite overall advancements in health care, mortality due to hepatic is constantly growing. More than 2 million people globally are estimated die each year from liver diseases, and current treatment offers little for its management. Thus, it essential find more effective less toxic pharmaceutical alternatives diseases....

Eclipta alba (L.) Hassk commonly known as bhringraj. It is mainly found spreading easily in moist grounds and is widely used for its nutritional values all over the world. The plant is used to treat different diseases in human in traditional medicine. The important pharmacological activities are hepatoprotection, antibacterial, analgesic, antidiabetic hair growth, etc. This paper explains the e...

The present study was conducted to evaluate the hepatoprotective activity of methanolic extract of aerial parts of Plumbago zeylanica in CCl4-induced hepatotoxicity in wistar rats. Silymarin (100mg/kg, p.o.) was given as reference drug. The extract of aerial parts of Plumbago zeylanica have shown very significant hepatoprotection against CCl4-induced hepatotoxicity in wistar rats by reducing se...