The rice leaffolder, Cnaphalocrocis medinalis Guenée (Lepidoptera: Pyralidae), is one of the most destructive pests of rice. Electrophysiological responses of this species to 38 synthetic volatiles known to be released from rice plants (Poaceae: Oryza spp.) were studied using the electroantennogram (EAG) method. Compounds that elicited the strongest EAG responses for each physiological conditio...

Action potential duration (APD) and conduction velocity restitution explain the dependence of these parameters on the previous diastolic interval (DI). It is considered to be an adaptive mechanism for preserving diastole at fast heart rates. Hypokalaemia is known to induce ventricular arrhythmias that could be prevented by heptanol, the gap junction uncoupler, mediated through increases in vent...

In this research, effect of bicomponent mixed surfactant was studied on drop interface coalescence phenomenon in ambient temperature. First basic chemical system was water and toluene and 0.01 gr of sodium dodecyle sulfate (SDS) and the second basic system was water and toluene and 0.01 gr of cethyl trimethy amonium bromide (CTAB). Various weight fractions of second surfactant including 2-hepta...

Background. The aim of this study was to test the hypothesis that electrical uncoupling and depression of the fast sodium channels have differential effects on propagation of the electrical impulse relative to the fiber orientation. Methods and Results. In a model of reentrant ventricular tachycardia (VT) (mean cycle length, 144±13 msec) around a ring of anisotropic myocardium in 10 Langendorff...

Signal transduction by the high-affinity IgE receptor (FcεRI) depends on membrane lipid and protein compartmentalization. Recently published data show that cells treated with 1-heptanol, a cell fluidizer, exhibit changes in properties. However, functional consequences of 1-heptanol-induced mast signaling are unknown. This study shows short-term exposure to 1-heptanol reduces thermal stability d...

Connexin43 (Cx43) is a major gap junction protein present in the Fischer-344 rat aorta. Previous studies have identified conditions under which selective disruption of intercellular communication with heptanol caused a significant, readily reversible and time-dependent diminution in the magnitude of alpha1-adrenergic contractions in isolated rat aorta. These observations have indentified a sign...

BACKGROUND The maintenance and termination of reentry arrhythmias are determined by tissue properties such as refractoriness and conduction velocity. Although the effects of Na(+) and K(+) channel block on electrophysiological properties and defibrillation threshold (DFT) have been studied, little is known about the effect of gap junction blockers on defibrillation and tissue electrophysiologic...

Gap junctions and sodium channels are the major molecular determinants of normal and abnormal electrical conduction through the myocardium, however, their exact contributions to arrhythmogenesis are unclear. We examined conduction and recovery properties of regular (S1) and extrasystolic (S2) action potentials (APs), S1S2 restitution and ventricular arrhythmogenicity using the gap junction and ...

A spectrophotometric study of the system heptanol—Nile red (NR)—water was carried out, where, for first time such studies, a non-colloidal surfactant that does not form micelles taken as surfactant. The dependence solubility NR on concentration heptanol in an aqueous solution studied. experiments were out at given chemical potential NR, which provided by excess solid phase NR. existence solubil...

Aqueous humor is secreted by the bilayered ciliary epithelium. Solutes and water enter the pigmented ciliary epithelial (PE) cell layer, cross gap junctions into the nonpigmented ciliary epithelial (NPE) cell layer, and are released into the aqueous humor. Electrical measurements suggest that heptanol reduces transepithelial ion movement by interrupting PE-NPE communication and that gap junctio...