BACKGROUND Traditional Chinese medicine (TCM) and Western medicine are both popular in Taiwan. Approximately 14.1% of Taiwanese residents use Western drugs and Chinese herbs concurrently; therefore, drug-herb interaction is critical to patient safety. This paper presents a new procedure for reducing the risk of drug interactions. METHODS Hospital computer systems are modified to ensure that d...

Herb-drug interaction strongly limits the clinical utilization of herbs and synthetic drugs. The inhibition of drug metabolism has been widely accepted to be an important reason for herb-drug interaction. The present study aims to investigate the inhibitory potential of herbal component scutellarein towards the metabolism of AZT which is the first U.S. government-approved antiretroviral drug fo...

CAM [12]. The patients under multiple systems of medication may have concerns about the possibility of the occurrence of polypharmacosis, thereby resulting in the interaction between drug molecules. The interactions may be apprehended and analyzed to be of drug-drug, herb-drug or food-drug varieties. In case of Drug-Drug Interactions the reaction mode is either pharmacodynamics or pharmacokinet...

Now a day’s people use herb or herbal remedies along with their medication in long term treatment of various disease. Concomitant use of herb and drug can interact with each other may cause herb drug interaction. The present study was designed to investigate the possible herb drug interaction between Momordica Chrantia Fruit Juice (MCFJ) and metformin. Metformin was given orally in two differen...

People misinterpret “natural” with “safe”. Unaware of the fact that herbal medicine contains pharmacological active constituents in unknown quantities; people use herbal medicinal products (HMPs) carelessly. In the present scenario, people use conventional medicines with herbal medicines that are used as complementary. Impact of co-administration of complementary herbal products with convention...

Objective: To evaluate the effect of NIPRD-AM1 on CYP3A4 in order to generate clinically significant data for its safe and efficacious use. Materials and Methods: NIPRD-AM1 is a phytomedicine developed from aqueous root extracts of Nauclea latifolia Smith (Rubiaceae) for the treatment of uncomplicated malaria. The effect of NIPRD-AM1 on CYP3A4 was measured with and without the addition of NIPRD...