PURPOSE To report the diagnosis, management, and outcome of acute retinal necrosis syndrome in children. METHOD Case series of three consecutive children aged 11 years and younger who were diagnosed with acute retinal necrosis. In addition to full ocular and systemic examinations, the children underwent vitreous biopsy (Patients 1 and 2) or aqueous tap (Patient 3) for polymerase chain reactio...

An approximately 1-year-old domestic rabbit showed severe neurologic signs with circling and turning somersaults. Histologically, a nonsuppurative meningoencephalitis with neuronal cell necrosis and numerous intranuclear inclusion bodies in neurons and glial cells was found. Electron microscopic examination revealed herpesvirus particles in affected cells. A human herpes simplex virus was ident...

INTRODUCTION Histopathologically, herpes simplex virus type 1 causes hemorrhagic necrosis. Overt hemorrhage is infrequent in herpes simplex virus encephalitis but can lead to poor outcomes. This report describes a successfully treated case of herpes simplex virus encephalitis associated with subarachnoid bleeding in which real-time polymerase chain reaction was useful for diagnosis. CASE PRES...

Cerebellar disorders due to herpes simplex virus (HSV) infection are rare and always associated with herpes simplex encephalitis. We report 2 cases of severe primary acute cerebellitis caused by HSV type 1 that were identified by nested polymerase chain reaction performed on cerebrospinal fluid samples.

Submit Manuscript | http://medcraveonline.com Abbreviations: ACE: Alternative Cellular Energy; HIV: Human Immunodeficiency Virus; HSV: Herpes Simplex Virus; HZV: Herpes Zoster Virus; HPV: Human Papillomaviruses; KELEA: Kinetic Energy Limiting Electrostatic Attraction; SCMV: African Green Monkey Simian Cytomegalovirus; CPE: Cytopathic Effect; CTL: Cytotoxic T Lymphocytes; CAM: Complementary and ...

Abstract A 39-year-old male without any preceding medical ailment presented with 12 day history of fever followed by behavioral changes left sided weakness. He was found to have Herpes Simplex Virus-1 encephalitis (polymerase chain reaction positive) and Magnetic Resonance Imaging finding asymmetrical frontotemporoparietal (right side affected more than side) involvement patchy enhancement atyp...

acyclovir (9-[2-hydroxyethoxymethyl] guanine) is an acyclic nucleoside analogue of guanosine which is a potent and selective antiviral agent. acycloviris converted to the monophosphate by thymidine kinase the virus-specific form of this enzyme and is subsequently converted to the triphosphate by the host cell kinase. acyclovir triphosphate inhibits viral dna-polymerase terminating the chain and...

INTRODUCTION Herpes simplex virus type 1 encephalitis presents acutely in patients who are immunocompetent. We report what we believe to be the first published case of a subacute course of herpes simplex virus type 1 encephalitis in a patient with asymptomatic chronic lymphocytic leukemia who subsequently developed multiple sclerosis. CASE PRESENTATION A 49-year-old Caucasian woman with a his...

OBJECTIVE To investigate the prevalence of herpes simplex virus (HSV), cytomegalovirus (CMV), and Epstein-Barr virus (EBV) in the semen of men with fertility problems. DESIGN A descriptive clinical study. SETTINGS Outpatient infertility clinic of a private hospital. PATIENT(S) One hundred thirteen men attending an infertility clinic in Athens. INTERVENTION(S) Semen samples were collecte...