conclusions herpes simplex virus was present in more patients with ms than healthy cases. hsv may be directly or indirectly associated with ms development. further comprehensive molecular studies are needed to confirm the etiopathologic association between hsv and ms disease. results totally, 63 (76.8%) patients with ms showed a history of hsv exposure by anti-hsv testing compared to 70 (78.7%)...

background :wide distribution and low half-life of acyclovir has led to a high dose consumption of the drug. recent studies have shown that encapsulation of acyclovir in nano-carriers can increase effectiveness and decrease its side effects. we investigated the inhibitory effect of acyclovir loaded nano-niosomes against herpes simplex virus type-1 (hsv-1) in cell culture.   methods : in-vitro c...

background: the present study sought to investigate molecular evidence for association between the presence of herpes simplex virus (hsv), cytomegalovirus (cmv), and epstein-barr virus (ebv) in crc and colorectal polyp by using the pcr method in iran. methods: in this analytical case-control study, we selected 15 patients with crc, 20 patients with colorectal polyp, and 35 patients without mali...

herpes simplex virus (hsv) is one of the common pathogenic viruses of humans bing. this study aimed to determin anti-herpes virus activity of mentha piperita extracts in vitro. mentha piperita extracts can inhibit hsv infection when the cells treated before viral adsorbtion. hsv-1 were also inhibited by menthol after viral adsorption. hsv-1 viral particles were directly inhibited and viral yiel...

objective herpes simplex virus (hsv), one of the most common sexually transmitted disease is a worldwide .this study aimed to prevalence of herpes simplex virus of pregnancy in iran. methods: we searched pubmed, scopus, ovid, science direct and national databases were searched: magiran, iranmedex and science information database (sid) up to october 2015.eventually, we included five studies that...

Background: Herpes simplex virus (HSV) encephalitis is the most common cause of sporadic encephalitis, with significant morbidity and mortality that are effectively reduced by antiviral treatment. Herpes simplex infection in pregnant women rarely results in encephalitis. The most common symptoms of a pregnant woman with herpes simplex infection are colds and skin vesicles. Herpetic encephalitis...

Brown alga, Turbinaria conoides was successively extracted with n-hexane, cyclohexane, methanol and ethanol:water (1:1). The extracts were evaluated for antibacterial and antifungal activities by disc diffusion method. Minimal inhibitory concentration was determined for active extracts by broth dilution method. The antiviral activity and cytotoxicity of the extracts were tested in human embryon...

    Acyclovir (9-[2-hydroxyethoxymethyl] guanine) is an acyclic nucleoside analogue of guanosine which is a potent and selective antiviral agent. Acycloviris converted to the monophosphate by thymidine kinase the virus-specific form of this enzyme and is subsequently converted to the triphosphate by the host cell kinase. Acyclovir triphosphate inhibits viral DNA-polymerase terminating the chain...

objective: herpes simplex virus (hsvs) is a widespread human infectious agent, responsible for persistent and latent infections. herpes simplex virus infections are usually continually recurrent in the normal population and represent a significant cause of complications in immunocompromised patients. materials and methods: in this study hsvs were propagated in bk cells and more than 502 sample...