Human breast cancer represents a group of highly heterogeneous lesions consisting of about 20 morphologically distinct subtypes with substantially different molecular and/or biochemical signatures, clinical courses, and prognoses. This study analyzed the possible correlation between the morphological presentations of breast cancer and two hypothesized models of carcinogenesis, in order to ident...

breast cancer is a major public health problem for women in the iran and many other parts of the world. dynamic contrast-enhanced magnetic resonance imaging (dce-mri) plays a pivotal role in breast cancer care, including detection, diagnosis, and treatment monitoring. but segmentation of these images which is seriously affected by intensity inhomogeneities created by radio-frequency coils, is a...

breast lesion segmentation in mr images is one of the most important parts of clinical diagnostic tools. pixel classification methods have been frequently used in image segmentation with two supervised and unsupervised approaches up to now. supervised segmentation methods lead to high accuracy, but they need a large amount of labeled data, which is hard, expensive, and slow to be obtained. on t...

Correspondence: Aysegul Sahin, M.D., University of Texas M. D. Anderson Cancer Center, Unit 85, 1515 Holcombe Boulevard, Houston, Texas 77030, USA. Telephone: 713-794-1500; Fax: 713-745-5704; e-mail: [email protected] Received November 2, 2005; accepted for publication March 16, 2006. ©AlphaMed Press 1083-7159/2006/$20.00/0 Abstract Benign breast diseases constitute a heterogeneous group of...

Human breast cancer represents a group of highly heterogeneous lesions consisting of about 20 morphologically and immnohistochemically distinct subtypes with substantially different prognoses. Our recent studies have suggested that all breast cancer subtypes, however, may share a common pathway, tumor cell budding from focally disrupted tumor capsules, for their invasion. The potential mechanis...

conclusion the possibility of malignancy is strongly indicated when additional nme lesions show linear or segmental enhancement on preoperative 3t dce-mri in patients with recently diagnosed breast cancer. results on histopathologic analysis of the 88 nme lesions, 73 (83%) were malignant and 15 (17%) were benign. lesion size did not differ significantly between malignant and benign lesions (p =...

conclusion non-mass-like lesions, lesions with focal or segmental distribution, with a “plateau” enhancement curve type were the most frequent findings of dcis lesions on mri. background adequate diagnosis of ductal carcinoma in situ (dcis) could lead to efficacious treatment. due to the fact that dcis lesions can progress to invasive carcinomas and that the sensitivity of the standard examinat...

Background: Throughout life period of female, breast is subjected to constant physical and physiological alterations that are related puberty, menstrual cycle, pregnancy, lactation, menopause. Benign diseases (BBD) constitute a heterogeneous group lesions which include developmental abnormalities, inflammatory granulomatous lesions, epithelial stromal proliferations, neoplasms.Methods: This pro...

objectives the aim of this study was to evaluate the value of diffusion weighted imaging in diffusion weighted imaging in distinguishing between in benign and malignant breast lesion methods there were 37 female patients with 47 lesions. sixty seven female subjectd (40 mean age ) ,age ranges 17-69 , with histopathologically proven breast lesions underwent dwi of breasts with a single shot echo ...