URING meiosis, homologous chromosomes normally pair with each other and separate whereas the members of pairs of non-homologous chromosomes assort independently of one another. This behavior is disturbed, however, in individuals carrying a translocation. It is well known that a t the first meiotic division separation of the four components of a translocation configuration may take place in a nu...

Alternate-1 and alternate-2 orientation of chromosomes, as well as the two types of adjacent orientation, were observed cytologically in the ring configurations of three reciprocal translocation heterozygotes of Gossypium hirsutum L. The observations indicate that the two types of alternate orientation should be characteristic of ring-forming translocations.

background: robertsonian translocations are structural chromosomal abnormalities caused by fusion of two acrocentric chromosomes. in carriers of such translocations, different modes of segregations would result in the formation of either balanced (alternate segregation mode) or unbalanced (adjacent 1, adjacent 2, and 3:1 segregation modes) gametes. in addition, there is an increased risk for im...