A method is demonstrated to optimize a stellarator's geometry eliminate magnetic islands and achieve other desired physics properties at the same time. For many quantities that have been used in stellarator optimization, including quasisymmetry, neoclassical transport, magnetohydrodynamic stability, it convenient use equilibrium representation assures existence of surfaces. However, this hides ...

A running debate in the recognition memory literature pits a long-standing theoretical framework known as signal detection theory against a popular multiple-process theory based on remember and know responses (Donaldson, 1996; Dunn, 2004; Gardiner & Gregg, 1997; Gardiner, Richardson-Klavehn, & Ramponi, 1998; Hirshman, 1998; Hirshman & Henzler, 1998; Hirshman & Master, 1997; Inoue & Bellezza, 19...

Aschenbach, William G., Richard C. Ho, Kei Sakamoto, Nobuharu Fujii, Yangfeng Li, Young-Bum Kim, Michael F. Hirshman, and Laurie J. Goodyear. Regulation of Dishevelled and -catenin in rat skeletal muscle: an alternative exercise-induced GSK-3 signaling pathway. Am J Physiol Endocrinol Metab 291: E152–E158, 2006. First published February 14, 2006; doi:10.1152/ajpendo.00180.2005.— catenin is a mu...

Coil complexity is a critical consideration in stellarator design. The traditional two-step optimization approach, which the plasma boundary optimized for physics properties and coils are subsequently to be consistent with this boundary, can result shapes cannot produced sufficiently simple coils. To address challenge, we propose method incorporate considerations of coil boundary. metrics compu...

Hotta, Kunihisa, Charles W. Emala, and Carol A. Hirshman. TNF-a upregulates Gia and Gqa protein expression and function in human airway smooth muscle cells. Am. J. Physiol. 276 (Lung Cell. Mol. Physiol. 20): L405–L411, 1999.—Chronic inflammation is a characteristic feature of asthma. Multiple inflammatory mediators are released within the asthmatic lung, some of which may have detrimental effec...

Hirshman, Carol A., Hideaki Togashi, Dan Shao, and Charles W. Emala. Gai-2 is required for carbachol-induced stress fiber formation in human airway smooth muscle cells. Am. J. Physiol. 275 (Lung Cell. Mol. Physiol. 19): L911–L916, 1998.—To determine which heterotrimeric G protein couples muscarinic receptors to stress fiber formation [measured by an increase in the filamentous (F)to monomeric (...

A self-consistent equilibrium calculation, valid for arbitrary aspect ratio tokamaks, is obtained through a direct variational technique that reduces the equilibrium solution, in general obtained from the 2D Grad–Shafranov equation, to a 1D problem in the radial flux coordinateρ. The plasma current profile is supposed to have contributions of the diamagnetic, Pfirsch–Schlüter and the neoclassic...

We present some evidence from the U.S. Census about the market concentration in the home appliances sector (e.g., four-firm concentration ratio and Herfindahl-Hirshman index) which suggests that competition in this sector, rather than being perfect, is better described by an oligopoly structure. We develop a general equilibrium three-sector growth model (home, market, appliances) where the pric...

We present a study of the linear properties ion-temperature gradient (ITG) modes with collisions modelled for first time by linearized gyrokinetic (GK) Coulomb collision operator (Frei et al. , J. Plasma Phys. vol. 87, issue 5, 2021, 905870501) in local limit. The is based on Hermite–Laguerre polynomial expansion perturbed ion distribution function applied to GK Boltzmann equation, yielding hie...

Yu, Haiyan, Nobuharu Fujii, Michael F. Hirshman, Jason M. Pomerleau, and Laurie J. Goodyear. Cloning and characterization of mouse 5 -AMP-activated protein kinase 3 subunit. Am J Physiol Cell Physiol 286: C283–C292, 2004. First published September 24, 2003; 10.1152/ajpcell.00319.2003.—Naturally occurring mutations in the regulatory -subunit of 5 -AMP-activated protein kinase (AMPK) can result i...