AIMS To define and group static and dynamic iliac crest histomorphometric parameters in women with established osteoporosis. METHODS Iliac crest biopsy specimens from 146 white women were sectioned undecalcified and examined using image analysis. RESULTS Five distinct groups were defined on the basis of histomorphometric changes in cell function: group 1, decreased osteoblastic and osteocla...

objective(s): the adverse effects of pyridaben on reproductive system in male animals are not well established. this study was designed to elucidate how pyridaben can effects the histomorphometric, hormonal alternations and reproductive functions of balb/c mice .   materials and methods : for this study, 80 adult and apparently healthy male balb/c mice were divided into three groups viz, contro...

BACKGROUND A study was designed to quantify the extent of porous osseointegration at the prosthesis-bone interface in the Prestige LP prosthesis containing a plasma-sprayed titanium coating. METHODS Using an anterior surgical approach, cervical disc arthroplasty was performed in 8 mature male goats at the C3-C4 segment, followed by implantation of the Prestige LP prosthesis. The vertebral spe...

Tetracyclines are considered potential medication for the treatment of osteoporosis. The aim of the present study was to investigate the effects of doxycycline on development of unfavorable changes in bone histomorphometric parameters induced by bilateral ovariectomy in rats. Doxycycline at a dose of 20 mg/kg po daily was administered for 28 days to bilaterally ovariectomized and sham-operated ...

Food intake of rats increases during pregnancy. This requires changes in the structure of the small intestine to absorb additional food. The aim of the present study was to investigate the morphological changes in the layers of small intestine in rats during pregnancy. Duodenum, jejunum and ileum of 18 pregnant Sprague-Dawley rats (day 7, 14 and 21 of pregnancy) were collected. Villous height a...

Enoxaparin sodium is a low-molecular-weight heparin. It is not clear whether the risk of development of osteoporosis after administration of low-molecular-weight heparins is lower than after administration of standard heparin. The aim of the present study was to investigate the effects of enoxaparin on histomorphometric parameters of bones in female Wistar rats (13-15 weeks old at the beginning...

statement of problem: the goal of bone regenerative therapy is to reconstruct the damaged tissues to initial condition, which seems so important in periodontoiogy and implantology. in such therapies, different biomaterials, with some advantages and disadvantages, may by use.purpose: the aim of this research was to evaluate the quality, bone trabecular density and thickness of newly forming bone...