paecilomyces sp, is a saprophytic fungus which has rarely been associated with human disease. we report the first case of invasive subcutaneous infection caused by this fungus in a 78-year-old female from damghan, iran, with diabetes and chronic renal failure. a biopsy provided an initial diagnosis of the mold in tissue. multiple positive fungal cultures which were obtained from the biopsied ti...

Penicilliosis is an opportunistic infection in HIV-infected and other immunocompromised patients mostly in Southeast Asia, Southern China, Hong Kong, and Taiwan, with respiratory manifestations in about one-third of patients. We report the case of a 26-year-old non-HIV immunocompromised patient presenting with an airway obstruction caused by penicilliosis, together with a review of the literatu...

background: kaposi’s sarcoma is a vascular malignancy, which frequently occurs among immunocompromised individuals such as transplant recipients and patients with acquired immunodeficiency syndrome. human herpesvirus 8 (hhv-8) is considered the etiological agent of all forms of kaposi’s sarcoma. though some seroepidemiological studies conducted on the prevalence of hhv-8 in iran, there are insu...

Abstract Nontuberculous mycobacteria can cause disseminated infections in immunocompromised patients and are challenging to treat because of antimicrobial resistance adverse effects prolonged multidrug treatment. We report successful treatment with bedaquiline, a novel antimycobacterial drug, as part combination therapy for 2 nontuberculous co-infected HIV.

BACKGROUND Long-term outcomes in non-HIV immunocompromised patients with disseminated Mycobacterium avium complex (dMAC) infections are unknown and the need for post-treatment secondary prophylaxis against MAC is uncertain in this setting. The objective of this study was to determine the need of continuing secondary anti-MAC prophylaxis in non-HIV patients after completing treatment of the prim...

Cryptococcosis is an important opportunistic fungal infection and also cause of death due to central nervous system disease among patients with human immunodeficiency virus worldwide. Most the cases occur in immunocompromised like HIV infected people, people organ transplants on immunosuppressants. Nowdays there increase cryptoccal meningitis diabetic patients. Current case series includes cryp...

Cryptococcal meningitis is a life-threatening condition caused by an invasive, opportunistic, encapsulated saprophytic fungus, either Cryptococcus neoformans or gattii most often in immunocompromised patients, especially those with human immunodeficiency virus (HIV). Overwhelming invasive infection of immunocompetent patients rather uncommon, and diagnosis challenging due to more indolent cours...

background: toxoplasma gondii , the obligate intracellular parasite is life threatening in aids patients. diagnosis of toxoplasmosis is based on serological methods especially increasing of igm and igg titers, but finding of parasite or its components (antigenemia) may be beneficial method in order to detection of acute toxoplasmosis in immunocompromised patients. methods: ninety-four serum sam...

Severe sepsis is more and more frequent, especially because of an increased rate of immunocompromised patients. Despite the improvement in the overall prognosis of HIV/AIDS patients and the improvement of global ICU care, the prognosis of HIV/ADS patients hospitalized in ICU with severe sepsis remained poor. This situation is partly due to the increased proportion of HIV/AIDS patients with limi...

Abstract Optic nerve tuberculoma is a rare extra-pulmonary manifestation of mycobacterial infection. It usually associated with HIV infected patients. Due to its clinical polymorphism, the diagnosis and management disease either in immunocompetent patients immunocompromised ones remains challenging. Herein, we discuss case 32-year-old patient no history immunodeficiency admitted for multifocal ...