In a recent paper Siegfried et al. 1 published a new sequence-­‐based structural RNA assay that utilizes mutational profiling to detect base pairing (MaP). Output from MaP provides information about both pairing (via reactivities) and contact (via correlations). Reactivities can be coupled to partition function folding models for structural inference 2 , while correlations can reveal pairs of s...

2. Livermore DM. Bacterial resistance: origins, epidemiology, and impact. Clin Infect Dis. 2003;36(Suppl 1):S11–23. DOI: 10.1086/344654 3. Sjölund M, Bonnedahl J, Hernandez J, Bengtsson S, Cederbrant G, Pinhassi J, et al. Dissemination of multidrug-resistant bacteria into the Arctic. Emerg Infect Dis. 2008;14:70–2. DOI: 10.3201/ eid1401.070704 4. Sellin M, Palmgren H, Broman T, Bergström S, Ols...

We have studied the time evolution of the power spectrum of XTE J1550-564, using X-ray luminosity time series data obtained by the Rossi X-Ray Timing Explorer satellite. A number of important practical fundamental issues arise in the analysis of these data, including dealing with time-tagged event data, removal of noise from a highly non stationary signal, and comparison of different time-frequ...

Eosinophilic esophagitis (EoE) is an emerging disease in both pediatric and adult patients. It is a chronic disease of the esophagus and refers to intense eosinophilic infiltration limited to the esophageal epithelium in the absence of gastroesophageal reflux disease. In most patients, EoE is thought to be part of an allergic response to food antigens or aeroallergens. One such trigger could be...

Documenting cultural life in contemporary Australia seems a fraught and daunting task, if not for the one-sided narratives so consistently reinforced through early scholarship, then at least due to geographical vastness diverse population that makes generalisation difficult. The arrival of Music City Melbourne: Urban Culture, History Policy is thus welcomed its resolute specificity unique histo...

Eosinophilic esophagitis (EoE) is an emerging disease in both pediatric and adult patients. It is a chronic disease of the esophagus and refers to intense eosinophilic infiltration limited to the esophageal epithelium in the absence of gastroesophageal reflux disease. In most patients, EoE is thought to be part of an allergic response to food antigens or aeroallergens. One such trigger could be...

morbidity of severe aortic regurgitation: a long-term follow up study. Circulation 1999;99:1851–1857. 31. Pellikka PA, Sarano ME, Nishimura RA, Malouf JF, Bailey KR, Scott CG, Barnes ME, Tajik AJ. Outcome of 622 adults with asymptomatic, hemodynamically significant aortic stenosis during prolonged follow-up. Circulation 2005;111:3290–3295. 32. Wolf PA, D’Agostino RB, Belanger AJ, Kannel WB. Pro...