Prior to 1938 no form of oral hormonal contraception was possible as none of the then availablehormones were active when given orally. The era of oral contraception commenced withthe reports of Pincus et al (3). The contraceptive pills used today contain a synthetic oestrogenand a synthetic progestational agent. Oestrone and oestradiol were available prior to 1938as esters but these were active...

a total number of 124 women of childbearing age attending a family planning clinic in teheran were investigated for the effects of contraceptive steroids and the intra-terine device on their hemoglobin concentration, packed cell volume, serum iron and serum tibc. a total of 42 women were used as control group of 42 women who were fitted with an intra-uterine device, 17 were studied for changes ...