hot spots are among the most serious operational issues in furnaces as they may result in the destruction of tubes. hence, it is essential to locate such hot spots precisely on the tube surfaces inside the industrial furnaces in order to secure a safe design and operation. in the current study, we have extended the model proposed by talmor in order to precisely locate the combustion hot spots o...

The M26 mutation in the ade6 gene of Schizosaccharomyces pombe creates a hot spot of meiotic recombination. A single base substitution, the M26 mutation is situated within the open reading frame, near the 5' end. It has previously been shown that the heptanucleotide sequence 5' ATGACGT 3', which includes the M26 mutation, is required for hot spot activity. The 510-bp ade6-delXB deletion encompa...

The variable (V) regions of immunoglobulin heavy and light chains undergo high rates of somatic mutation during the immune response. Although point mutations accumulate throughout the V regions and their immediate flanking sequences, analysis of large numbers of mutations that have arisen in vivo reveal that the triplet AGC appears to be most susceptible to mutation. We have stably transfected ...

In parallel systems it is possible for several processors to request concurrent access to a shared data structure such as a synchronization variable. Such an access pattern causes what is known as hotspot contention. In shared-memory multiprocessor systems that use a multistage interconnection network, hot-spot contention may result in "tree saturation" that degrades the system performance. It ...

In the context of protein-protein interactions, the term "hot spot" refers to a residue or cluster of residues that makes a major contribution to the binding free energy, as determined by alanine scanning mutagenesis. In contrast, in pharmaceutical research, a hot spot is a site on a target protein that has high propensity for ligand binding and hence is potentially important for drug discovery...

BACKGROUND Manual counting of microvessels is subjective and may lead to unacceptable interobserver variability, which may explain conflicting results. AIMS To develop and test an automated method for microvessel counting and objective selection of the hot spot, based on image processing of whole sections, and to compare this with manual selection of a hot spot and counting of microvessels. ...

IEEE 802.11 WLAN technology has become an inexpensive, yet powerful access technology that is targeted at mobile users that remain within reach of the hot-spot. Such hot-spots are usually provided by a wireless Internet service provider (WISP) in locations often frequented by travelers. Past measurements have shown that WLAN is even able to support mobile users passing by without stopping and “...

A composite transposon, Tn4731, associated with IS630 has been shown to transpose preferentially to 5'-TA-3' sequences that are located at two sites in a rho-dependent transcription terminator in plasmid ColE1 in Escherichia coli (T. Tenzen, S. Matsutani, and E. Ohtsubo, J. Bacteriol. 172:3830-3836, 1990). Here we demonstrated that Tn4731 preferentially transposes to TA sequences at four sites ...

Certain genomic loci, termed hot spots, are predisposed to undergo genetic recombination during meiosis at higher levels relative to the rest of the genome. The factors that specify hot-spot potential are not well understood. The M26 hot spot of Schizosaccharomyces pombe is dependent on certain trans activators and a specific nucleotide sequence, which can function as a hot spot in a position- ...