BACKGROUND Although unsaturated fatty acids such as eicosapentaenoic acid (EPA, C20:5n-3), docosahexaenoic acid (DHA, C22:6n-3) and arachidonic acid (ARA, C20:4n-6), collectively known as the highly unsaturated fatty acids (HUFA), play pivotal roles in vertebrate reproduction, very little is known about their synthesis in the ovary. The zebrafish (Danio rerio) display capability to synthesize a...

There is a wide spectrum of conditions in which deficiencies of highly unsaturated fatty acids (HUFA) appear to play a role (Glen et al, 1999). This includes atopic (allergic) conditions such as eczema and asthma as well as psychiatric disorders such as schizophrenia and depression. The focus here is on the role of HUFA in three common learning and behavioural disorders dyslexia, dyspraxia and ...

The objective of this study was to evaluate the combined effects of thermal acclimation and n-3 highly unsaturated fatty acids (n-3 HUFA) content of the food source on the aerobic capacities of fish in a thermal changing environment. The model used was the golden grey mullet Liza aurata, a species of high ecological importance in temperate coastal areas. For four months, fish were exposed to tw...

Delta6 desaturase (D6D), the rate-limiting enzyme for highly unsaturated fatty acid (HUFA) synthesis, is induced by essential fatty acid-deficient diets. Sterol regulatory element-binding protein-1c (SREBP-1c) in part mediates this induction. Paradoxically, D6D is also induced by ligands of peroxisome proliferator-activated receptor alpha (PPARalpha). Here, we report a novel physiological role ...

Running title: HUFA gene expression in salmon fed vegetable oil Abstract Fish are an important dietary source of the long-chain C 20 and C 22 highly unsaturated fatty acids (HUFA), arachidonate (20:4n-6), eicosapentaenoate (20:5n-3) and docosahexaenoate (22:6n-3), that are crucial to the health of higher vertebrates and that can be beneficial in human diets. Δ5 and Δ6 fatty acid desaturases, an...

An experiment was conducted in aquaria with channel catfish (Ictalurus punctatus) to determine the efficacy of augmenting fillets with conjugated linoleic acid (CLA) and omega-3 highly unsaturated fatty acids (n−3 HUFA) by feeding diets amended with products containing high levels of these nutrients. Refined menhaden fish oil at 1.5% of diet supplied the n−3 HUFA. CLAwas used at dietary levels ...

A quantitative approach is presented to evaluate fatty acid incorporation in fish. Fatty acid composition of European sea bass juvenile was studied during an experiment using 6 isoproteic (54%) and isolipidic (18%) diets containing 0.23, 0.56, 0.72, 0.86, 1.01 and 1.86% DM n-3 highly unsaturated fatty acids (n-3 HUFA). Whole body fatty acid compositions were studied at the beginning and after 5...

Globally, wild seahorse populations are threatened due to, habitat destruction and unsustainable human exploitation among others. Furthermore, aquaculture-based mass-scale rearing is still uncommon due to the low survival rates of seahorse juveniles and exceptionally high feed costs. Previous studies have demonstrated the importance of both highly unsaturated fatty acid (HUFA) supplies and a co...