background: the study aimed to examine the association between human leukocyte antigen (hla) class ii allele frequencies and breast cancer in iranian women. methods: a total of 100 patients with pathologically proven breast cancer who referred to cancer institute were randomly selected and compared with a group of age matched healthy blood donors (n = 80). hla class ii alleles were determined b...

conclusions according to the low prevalence of hcmv in oscc, it seems that this virus plays a minor role in this kind of cancer at least in southeast of iran. more comprehensive studies are needed to investigate the oncomodulatory effect of this virus on oscc. results the mean age of the patients (66.7% female and 33.3% male) was 58.6 years. only three cases (6.3%) of the grade i, oscc biopsies...

background recombinant human erythropoietin (rhuepo) treatment can increase hemoglobin levels and decrease transfusion requirements. this study aims to investigate how blood transfusion influences hemoglobin levels in patients receiving rhuepo for 12 weeks. materials and methods this was a case-control study of 60 patients less than 15 years with anemia and a solid tumor in any location between...

human papilloma virus causes benign and malignant abnormalities in different part of the body. the link between high risk types of hpv and some anogenital and aerodigestive tract cancer is well established. oral hpv infection plays a role in developing oropharyngeal squamous cell carcinoma. we studied the prevalence of oral hpv in healthy individuals and its relative risk factors.saliva samples...

conclusions imp3 immunoreactivity was associated with poor differentiation of tumor yet not associated with tumor size depth of invasion or lymph node involvement. results immunoreactivity pattern of imp3 was cytoplasmic in different clinicopathologic findings. among different clinicopathologic findings, we found a statistical relationship between tumor differentiation and imp3 (p = 0.047); so ...

abstract background and aims: the human papilloma virus was introduced as the major etiological agent in outbreak of cervical cancer in 1970. since it is impossible to recognize these viruses and these types using the serological tests and cell culture, molecular methods such as pcr are of great importance. therefore, in this study, our goal was to use a multiple specific pcr assay on l1 and e6...

  Human papillomavirus (HPV) is one of the most common causes of sexually transmitted diseases worldwide and is the etiological agent of cervical and other anogenital malignancies. Since HPVs have been shown to possess oncogenic potential, an association between HPV infection and prostatic cancer (PCa) has been suggested. There are conflicting reports on the impact of HPV infection on the deve...

few studies have been conducted on the causative factors associated with the development of cancer. infection by high risk human papillomaviruses (hpvs) have been implicated as causative agents in a variety of cancers. hpv is capable of evading immune system and establishing persistent infections. prolonged infection and lesion maintenance are associated with higher risk of neoplastic progressi...

background: breast cancer is the malignancy in humans and other mammals. several risk factors are involved in their appearance such as higher hormone levels and obesity. identification of a mouse mammary tumor virus supports a viral etiology for breast tumors in animals. viruses have been implicated in the development of various cancers, but viral induction for formation breast cancer is contro...