نتایج جستجو برای: human iron requirement
تعداد نتایج: 1915833 فیلتر نتایج به سال:
Cancer cells have a high iron requirement and many experimental studies, as well as clinical trials, have demonstrated that iron chelators are potential anti-cancer agents. The ligand, 2-benzoylpyridine 4-ethyl-3-thiosemicarbazone (Bp4eT), demonstrates both potent anti-neoplastic and anti-retroviral properties. In this study, Bp4eT and its recently identified amidrazone and semicarbazone metabo...
It is well-known that deficiency or over exposure to various elements has noticeable effects on human health. The effect of an element is determined by several characteristics, including absorption, metabolism, and degree of interaction with physiological processes. Iron is an essential element for almost all living organisms as it participates in a wide variety of metabolic processes, includin...
Glutamine 5-phosphoribosyl-1-pyrophosphate amidotransferase (EC 2.4.2.14), amidophosphoribosyltransferase, was partially purified from human placenta. Upon exposure to oxygen, both the glutamine and ammonia activities were lost in parallel. Inactivation by oxygen increased as the temperature of incubation rose and the partial pressure of oxygen increased. Molecular oxygen rather than a radical ...
The ability of pathogenic microorganisms to assimilate sufficient nutrients for growth within their hosts is a fundamental requirement for pathogenicity. However, certain trace nutrients, including iron, zinc and manganese, are actively withheld from invading pathogens in a process called nutritional immunity. Therefore, successful pathogenic species must have evolved specialized mechanisms in ...
Review: The Potential of the Common Bean (Phaseolus vulgaris) as a Vehicle for Iron Biofortification
Common beans are a staple food and the major source of iron for populations in Eastern Africa and Latin America. Bean iron concentration is high and can be further increased by biofortification. A major constraint to bean iron biofortification is low iron absorption, attributed to inhibitory compounds such as phytic acid (PA) and polyphenol(s) (PP). We have evaluated the usefulness of the commo...
Antiviral treatment of hepatitis C virus in thalassemia has raised concerns of ribavirin-induced hemolysis and increased iron loading. This study examined the change in liver iron concentration, transfusion requirement, virological response, and iron-related toxicities after pegylated interferon alpha-2a/ribavirin treatment in patients with thalassemia. Median transfusions increased by 44%. How...
Iron regulatory proteins (IRP1 and IRP2) are RNA-binding proteins that bind to specific structures, termed iron-responsive elements (IREs), that are located in the 5'- or 3'-untranslated regions of mRNAs that encode proteins involved in iron homeostasis. IRP1 and IRP2 RNA binding activities are regulated by iron; IRP1 and IRP2 bind IREs with high affinity in iron-depleted cells and with low aff...
The dietary iron requirement for normal growth and optimum hematological values and bioavailability was determined for channel catfish Ictalurus punctatus fingerlings using eggwhite based diets supplemented with 0,5,10,20,60, and 180-mg ironkg from iron methionine or 20, 60, and 180-mg ironkg from iron sulfate. The basal diet which contained 9.2-mg ironkg, 34% crude protein and 3.1 kcal of dige...
نمودار تعداد نتایج جستجو در هر سال
با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید