background: visceral leishmaniasis (vl), caused by leishmania infantum , is a life-threatening vector-borne parasitic disease is distributed in some parts of the world. the disease is endemic in some parts of iran. this study was aimed to determine the seroprevalence of vl among children and domestic dogs (as a reservoir of the parasite) in dehloran, west of iran material and methods: this cros...

visceral leishmaniasis (vl) or kala-azar is considered as a parasitic disease caused by the species of leishmania donovani complex which is intracellular parasites. this systemic disease is endemic in some parts of provinc-es of iran. the aim of this study was to determine the seroprevalence of vl in qom province, central iran using di-rect agglutination test (dat).overall, 1564 serum samples (...

abstract introduction: this study was conducted to detect asymptomatic cases of visceral leishmaniasis in human and dog, using pcr and serology methods in darab, fars province. material and methods: in this descriptive cross-sectional survey, blood samples were randomly collected from all children aged 10 years old; 10% of the adults and 20% of the dog owners were investigated. to determine the...

background: parasitological methods for the diagnosis of visceral leishmania-sis (vl) require invasive procedures, so serological and molecular approaches have been developed but are not generally applicable in the field. we evaluated a loop mediated isothermal amplification (lamp) assay using blood from vl pa-tients and compared it to nested pcr. methods: forty-seven subjects with clinical fea...

Leishmaniasis - human immunodeficiency virus (HIV) coinfection can manifest itself as tegumentary or visceral leishmaniasis. Almost 35 countries have reported autochthonous coinfections. Visceral leishmaniasis is more frequently described. However, usual and unusual manifestations of tegumentary leishmaniasis have been reported mainly in the Americas, but the real prevalence of Leishmania infec...

BACKGROUND The early and correct diagnosis of human leishmaniasis is essential for disease treatment. Another important step in the control of visceral leishmaniasis is the identification of infected dogs, which are the main domestic reservoir of L. infantum. Recombinant proteins and synthetic peptides based on Leishmania genes have emerged as valuable targets for serodiagnosis due to their inc...

Leishmania infantum is the obligatory intracellular parasite of mammalian macrophages and causes zoonotic visceral leishmaniasis (ZVL). The presence of infected dogs as the main reservoir host of ZVL is regarded as the most important potential risk for human infection. Thus the prevention of canine visceral leishmaniasis (CVL) is essential to stop the current increase of the Mediterranean visce...

INTRODUCTION Visceral leishmaniasis is the most severe clinical form of leishmaniasis and is often fatal without proper treatment. Therefore, early and accurate diagnosis is important, but often difficult in endemic areas. OBJECTIVE The aim was to evaluate a direct agglutination test as a potential visceral leishmaniasis diagnostic method in endemic areas of Venezuela. MATERIALS AND METHODS...

background : visceral leishmaniasis (kala-azar) is an endemic disease in some areas of iran. a cross- sectional study was conducted for sero-epidemiological survey of visceral leishmaniasis (vl) in baft district from kerman province, southeast of iran. methods: blood samples  were  collected  from children  up to 12 years old and 10% of adult population from baft villages with a multi-stage ran...

Human leishmaniasis is a spectral disease that includes asymptomatic self-resolving infection, localized skin lesions, and progressive visceral leishmaniasis. With some overlap, visceral and cutaneous leishmaniasis are usually caused by different species of Leishmania. This review focuses on host responses to infection with the species that cause visceral leishmaniasis, as they contrast with sp...