نتایج جستجو برای: hydrogel hypothesis
تعداد نتایج: 230155 فیلتر نتایج به سال:
BACKGROUND We previously demonstrated that topical cutaneous application of CO2, by means of a hydrogel in which the CO2 readily dissolves, increases blood flow and oxygen dissociation from hemoglobin in the soft tissues surrounding bone. In the present study, we utilized a rat fracture model to test the hypothesis that application of this treatment to fractured limbs would accelerate fracture ...
OBJECTIVES/HYPOTHESIS The purpose of this study was to investigate the regenerative efficacy of an injectable hyaluronic acid/mildly cross-linked alginate hydrogel (HA/ALG hydrogel) containing human adipose-derived mesenchymal stem cells (hAdMSCs) for vocal fold (VF) wound healing. STUDY DESIGN Animal research. METHODS HA/ALG hydrogel containing hAdMSCs was injected into the VFs of rabbits ...
BACKGROUND AND PURPOSE Some patients are at high risk of aneurysm recurrence after endovascular treatment: patients with large aneurysms (Patients Prone to Recurrence After Endovascular Treatment PRET-1) or with aneurysms that have previously recurred after coiling (PRET-2). We aimed to establish whether the use of hydrogel coils improved efficacy outcomes compared with bare platinum coils. M...
The repair of peripheral nerve injuries is still one of the most challenging tasks and concerns in neurosurgery. Effect of methylprednisolone-laden hydrogel loaded into a chitosan conduit on the functional recovery of peripheral nerve using a rat sciatic nerve regeneration model was assessed. A 10-mm sciatic nerve defect was bridged using a chitosan conduit (CHIT/CGP-Hydrogel) filled with CGP-h...
Wharton’s jelly mesenchymal stem cells (HWJMSCs) hold promise for myocardial regeneration, but optimal treatment regimen (preferably with a growth factor) is required to maximize functional benefits. The aim of this study was to explore the cardioprotective and angiogenesis effects of HWJMSCs combined with insulin-like growth factor-1 (IGF-1) in the treatment of acute myocardial infarction. Th...
A new way is demonstrated to develop a bio-inspired coacervate hydrogel by following catechol chemistry showing injectable and re-moldable physical properties. The formed coacervate shows potential long-term stability under water. Depending on pH, formation of the coacervate has been verified which is confirmed by XPS and zeta potential measurements.
conclusions this study showed that compared to standard drug treatment, treatment with hydrogel containing peptide had substantial antibacterial effects on s. aureus wound infections in mice. results the highest and lowest numbers of wounds were observed on day 2 in the negative and positive control groups, respectively. during the 8-day period, the positive control and hydrogel containing pept...
cell-based biosensors have become a research hotspot in biosensors and bioelectronics fields. the main feature of cell-based biosensors is the immobilization of living cell on the surface of transducers. different types of polymers which are used as scaffolds for cell growth should be biocompatible and have reactive functional groups for further attachment of biomolecules. in this work, the cel...
Polyacrylic acid/ octavinyl polyhedral oligomeric silsesquioxane, nanocomposite hydrogel with 3-D network was synthesized via radical polymerization. Octavinyl polyhedral oligomeric silsesquioxane was used as crosslinker and nanofiller simultaneously in the preparation of the hydrogel. Hydrogel adsorption performance was determined by adsorption of methylene blue. The adsorption capacity was ev...
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