The aim of the present study was to investigate the relationship between the polar surface area and other molecular properties of the model drugs and their transdermal permeability across the rat skin. Few model drugs which are weakly acidic (ibuprofen, aceclofenac and glipizide) and weakly basic (olanzapine, telmisartan and sildenafil citrate) were selected for the study based on Polar surface...

3D modeling of Pd/α-Al2O3 hollow fiber membrane by using computational fluid dynamic for hydrogen separation from H2/N2 mixture was considered in steady and unsteady states by using the concept of characteristic time. Characteristic time concept could help us to design and calculate surface to volume ratio and membrane thickness, and adjust the feed conditions. The contribution of resistance be...

It is shown that an electrodeposited Zn-Ni-Cd alloy coating produced from sulfate electrolyte inhibits the discharge of hydrogen on carbon steel. The newly developed ternary alloys have approximately ten times higher corrosion resistance when compared to a Zn-Ni alloy. Hydrogen permeation characteristics of Zn-Ni-Cd alloy coatings were studied and compared with those of a bare and a Zn-Ni alloy...

A consistent description of the hydrogen permeation through metal membrane based on hydrogen chemical potential proposed has been explained in detail. The hydrogen flux is proportional to the PCT factor, fPCT, consistently, which reflects the shape of the pressure-composition-isotherm (PCT curve) of the material. In addition, in view of the PCT factor, fPCT, and the ductile-to-brittle transitio...

There seems some underlying technological interest in recent developments (1-9) in palladium alloy systems because of the possibilities of developing palladium alloys with improved characteristics for use as diffusion membranes for hydrogen purification and allied purposes (10). In addition to the important issues of surface kinetics and membrane thickness, other key factors for improved diffus...

This study assessed surface treatment techniques applicable to welded joints of stainless steel pipes and vessels for a hydrogen-permeation barrier. Specifically investigated was electrolytic polishing using electrolyte compositions consisting sulfuric acid, phosphoric methane-sulfonic acid promote uniform passive film formation on type 304 surface. also examined oxidation combination chemical ...

Three different approaches to detecting hydrogen in helium streams were assessed: thermal conductivity, atmospheric sampling using a mass spectrometer, and permeation through a palladium/silver membrane. The thermal conductivity detection system utilized an assembly of four cells fitted with filaments wired to make a Wheatstone bridge. Pure helium flowed through two of the cells. Helium contain...