BACKGROUND Atazanavir plus raltegravir 300/400 mg twice daily is being explored as a ritonavir- and nucleoside-sparing treatment strategy. The pharmacokinetics and safety of this combination in healthy individuals were evaluated. METHODS A total of 22 healthy individuals received raltegravir 400 mg on days 1-5, atazanavir 300 mg on days 6-12 and atazanavir plus raltegravir 300/400 mg on days ...

Carnation (Dianthus caryophyllus L.) is valuable in terms of production and exports in the world. Increased vase life of cut flowers is an important factor for their market acceptability. For this purpose this study was carried out to examine the effect of plant essential oils as compared to 8-hydroxy-quinoline sulfate on the control of bacteria population and the longevity of carnation cut flo...

An experiment was conducted to examine the effects on mortality, production performance, water intake (WI), and organ weight of Satureja khuzistanica essential oil (SkEO) using 720 1-day-old Arian broiler chicks in a 42-day trial. Experimental treatments were addition of 0 (control(-)), 200, 300, 400, and 500 mg/L SkEO or 500 mg/L polysorbate 80 (control(+)) into drinking water. The birds were ...

Effects of Hyoscyamus niger L on central nervous system have been known for many years. The effects of methanolic extract of H. niger L. on seizures induced by picrotoxin was studied in mice in this investigation. In this study 7 groups of animals pretreated with methanolic extract of the plant (12.5, 25, 50, 100, 200, 300, 400 mg/kg/i.p.), 20 minutes prior to the picrotoxin (12 mg/kg/ i.p.)--i...

The anaerobic digestion of sewage sludge is highly sensitive to high zinc concentrations. Although sulfate-reducing bacteria (SRB) activity can negatively affect methanogenesis, SRB-mediated metal sulfide precipitation alleviate toxicity. A series mesophilic batch experiments was performed for the biomethane potential three different samples 74 days using background content, alone or in combina...

this study was carried out to evaluate the effects of satureja khuzistanica essential oils (skeo) on performance, serum metabolites and differential counts of white blood cells in broiler chickens. a total of 280 one-day-old straight-run cobb 500 broiler chickens were allocated into seven treatment groups with four replicates of 10 birds each from day 1 to 42 of age. the birds were continuously...

Water is an essential nutrient for feedlot cattle. Drinking water may contain a variety of compounds. The important question is to what degree these substances impact water palatability and cattle health. The NRC in 1974 published limits for some potential problem causing substances in drinking water. Recommended safe upper limits for nitrate, sulfate, and total dissolved solids (TDS) were 440,...

BACKGROUND Myrtus communis L. has a folkloric repute for the management of diarrhea and dysentery in different parts of the world. However, the safety and efficacy of the leaf extract have not been scientifically validated in animal model. This study was, therefore, aimed to investigate the antidiarrheal effect of 80% methanol extract (80ME) and solvent fractions of the leaves of Myrtus communi...