BACKGROUND Conflicting views exist over whether responsiveness of the airways to hypertonic saline relates to non-specific bronchial hyperresponsiveness measured by histamine or methacholine challenge. The bronchoconstrictor responses to exercise and hypertonic saline are reported to be closely related, but the relationship between the symptoms of exercise induced asthma and airway responsivene...

hypertonic saline solution can absorb part of the intracellular fluid volume into the extracellular space. the effects of this solution on the cardiovascular system are increased coronary flow and increased left ventricular contraction, without sympathetic system activation. this study was designed to assess the effects of hypertonic saline solution in open heart surgery and to compare it with ...

BACKGROUND Inhaled hypertonic saline is used for bronchial challenge and sputum induction in patients with chronic obstructive pulmonary disease (COPD). We studied the effects of saline aerosol inhalation before each exercise session in an 8-week pulmonary rehabilitation program. METHODS This was a double-blind randomized parallel controlled trial, conducted at an out-patient clinic. Sixty-ei...

Cytotoxic brain edema—swelling of nerve and glial cells—is among the very early pathophysiologic sequelae of focal cerebral ischemia. Once cell swelling has exhausted the cerebral compliance, intracranial pressure increases and, thereby, causes secondary ischemia. Hypertonic solutions, mannitol in particular, have long been used to reduce intracranial pressure. More recently, hypertonic saline ...

background: haemonchosis has a negative effect on the farming industry throughout the world, especially in the tropic and sub-tropic countries. the present study was carried out to differentiate haemonchus species from its main hosts in iran, including sheep, goat and camel.   methods: the identification took place based on the morphometrics of the spic-ules and molecular characters. two hundre...

The efficacy of three hypertonic saline solutions for treating dialysis-induced hypotension in a randomized, blinded, crossover clinical trial of 10 patients (a minimum of three cycles per solution) was compared. Dialysis-induced hypotension, defined as a decrease in systolic blood pressure of at least 10 mm Hg or systolic blood pressure less than 100 mm Hg, was treated with an iv bolus of eith...