A case of adult hypertrophic pyloric stenosis presented in an older female with no apparent predisposing factors which might be likely to precipitate the condition. There was a history of chronic dyspepsia and occasional episodes of vomiting. No contributory medical history was identified. Barium swallow and follow through showed a markedly reduced emptying time of the stomach. A partial gastre...

The birth of a normal infant to a woman with Zollinger-Ellison syndrome is described. The cord blood serum gastrin was very elevated. This suggests that maternal gastrin can cross the placenta, a fact previously in doubt in man. The infant did not develop congenital hypertrophic pyloric stenosis. This is further evidence that raised blood gastrin in utero is not an important causative factor in...

The development of congenital hypertrophic pyloric stenosis concurrently in both sibs of uniovular, as well as binovular, twin pregnancies is well documented and has been the subject of numerous reviews (Metrakos, 1953; MacMahon and McKeown, 1955). The condition has also been described in 3 (Cameron, 1955), 4 (Gailey, 1948), and even 5 sibs (Benson, 1970) in the same family. This is the first r...

A 20-day-old girl presented with increasing projectile vomiting over a period of one week and progressive weight loss. The diagnosis of hypertrophic pyloric stenosis (HPS) was made by sonography (Length of pyloric channel: 22 mm; muscle thickness: 5 mm). Open standard pyloromyotomy was performed. The postoperative course uneventful. On the 50th postoperative day, the girl was readmitted with pr...

MANCHESTER, R.C. (1945) Chronic haemolytic anaemia with paroxysmal nocturnal haemoglobinuria. Ann. intern. Med. 23, 935. MARKS, J. (1949) The Marchiafava Micheli syndrome. Quart. J. Med. 18, 105. NUSSEY, A.M. & DAWSON, D.W. (1956) Paroxysmal nocturnal haemoglobinuria. Case study, including evidence of affection of the marrow in the disease. Blood, 11, 757. SCOTT, R.B., ROBB-SMITH, A.H.T. & SCOW...

Szilagyi and McGraw in 1943 aptly pointed out that 'When a disease has ceased to be a therapeutic problem, scientific interest in it is likely to wane. Not infrequently successful measures of treatment are devised before the fundamental problems of a disease have been solved, and in such instances the consequent lack of interest will be reflected in the neglect of the related, less practical bu...

Both congenital and adult types of hypertrophic stenosis of the pylorus are recognized. The congenital variety has an incidence of 5 per 1000 male births and 1 per 1000 female births in the general population of England (Carter, 1967), but it is less frequent in Negroes and in Asiatics (Donovan and Stanley-Brown, 1962; Swan, 1961). Both environmental and genetic factors seem to operate in the a...

We present 40 patients operated consecutively for pyloric stenosis during an 8-year period (1981-88). The most common symptom was projectile vomiting, which occurred in 92.5% of the cases. On examination only three patients had a palpable hypertrophic pylorus. In 39 patients, a preoperative x-ray examination with contrast was necessary to confirm the diagnosis. A pyleromyotomy was performed in ...