INTRODUCTION Hypnotics and sedatives, especially benzodiazepines and Z-drugs, are frequently prescribed for longer periods than recommended-in spite of potential risks for patients. Any intervention to improve this situation has to take into account the interplay between different actors, interests and needs. The ultimate goal of this study is to develop-together with the professionals involved...

The Spanish Society of Critical Care Medicine (SEMICYUC) has recently published an updated version of Quality Indicators in Critical Care. Daily sedative interruption is included among them. As this practice is controversial, research studies are revised and guidelines for its implementation are proposed.

Anticholinergic and sedative medications are commonly used in older adults and are associated with adverse clinical outcomes. The Drug Burden Index was developed to measure the cumulative exposure to these medications in older adults and its impact on physical and cognitive function. This narrative review discusses the research and clinical applications of the Drug Burden Index, and its advanta...

BACKGROUND Recent studies suggest an increased risk of adverse mental health outcomes among young adults who were born preterm. These studies have been based mainly on hospital data, thus missing large numbers of mental health problems that do not require inpatient treatment. We used national outpatient and inpatient pharmacy data to evaluate whether individuals who were born preterm were more ...

PURPOSE The study reported here aimed to identify current sedation practice among general dental practitioners (GDPs) and specialist dental practitioners (SDPs) in Jordan in 2010. METHODS Questionnaires were sent by email to 1683 GDPs and SDPs who were working in Jordan at the time of the study. The contact details of these dental practitioners were obtained from a Jordan Dental Association l...

The principle aims of pre-hospital care are to preserve life, minimise complications resulting from injury and reduce pain and suffering (1).To achieve this, the pre-hospital practitioner should be confident in the safe use of a limited range of analgesic and sedative drugs (1,2). In this article, a summary of effective and safe techniques for analgesia and sedation in both the civilian and mil...

1-Benzyl-2-methyl-5-methoxytryptamine has been reported, on the basis of indirect evidence, to inhibit monoamine oxidase. More direct experiments, however, demonstrate that the drug is devoid of the ability to block monoamine oxidase in brain in vitro or in vivo.

The pattern of drag use was studied in 213 heroin addicts, constituting 80.7% of the patient population attending ABHAY-II Deaddication Cum Rehabilitation Centre. All heroin addicts were male and 98.6% of all had consumed or have been consuming other drugs concurrently. Tobacco, cannabis and alcohol were the drugs commonly used by the addicts. The mean age for begining tobacco consumption was l...